Synthesis of Substituted 2-Aminoquinoline-1-oxides by Reductive Cyclization of Substituted 3-(2-Nitrophenyl)acrylonitriles
An approach to the class of 2-aminoquinoline-1-oxides is given based on reductive cyclization of appropriate substituted 3-(2-nitrophenyl)acrylonitriles.Thus, 2-nitrobenzylidene compounds 1a-d have been reductively cyclized by H2/PtO2 or H2/Pd-C under nor
Sicker, D.,Wilde, H.
p. 76 - 80
(2007/10/02)
Preparation electrochimique de derives de la quinoleine. II. Electroreduction d'o-nitrobenzylidenes substitues
Quinoline N-oxydes and N-hydroxyquinolones have been prepared by controlled potential electrolysis of o-nitrobenzylidenes: o-NO2-C6H4-CH=CX2, o-NO2-C6H4-CH=CRX, o-NO2-C6H4-CH=CXY (X and Y being electron withdrawing groups: CO2Et, CN, CONH2, COPh).As a gen
Chibani, A.,Hazard, R.,Jubault, M.,Tallec, A.
p. 795 - 802
(2007/10/02)
A BASE-CATALYSED REACTION OF ARYLIDENEMALONONITRILE WITH 2,1-BENZISOXAZOLES
Quinoline-N-oxide derivatives were prepared in good yields by a triethylamine-catalysed reaction of arylidenemalononitrile with 2,1-benzisoxazoles.