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N-BOC-3-AMINO-4-CHLOROBENZOIC ACID is a chemical compound with a molecular formula C12H13ClNO4. It is a derivative of 3-amino-4-chlorobenzoic acid that features a tert-butoxycarbonyl (BOC) protecting group attached to the amino group. N-BOC-3-AMINO-4-CHLOROBENZOIC ACID is characterized by its white to off-white solid appearance and stability under normal conditions. It is a versatile building block in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds, and serves as a reagent in organic chemistry, particularly for the formation of amide bonds.

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  • 160450-12-4 Structure
  • Basic information

    1. Product Name: N-BOC-3-AMINO-4-CHLOROBENZOIC ACID
    2. Synonyms: BOC-3-AMINO-4-CHLOROBENZOIC ACID;N-BOC-3-AMINO-4-CHLOROBENZOIC ACID
    3. CAS NO:160450-12-4
    4. Molecular Formula: C12H14ClNO4
    5. Molecular Weight: 271.7
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 160450-12-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 352.4 °C at 760 mmHg
    3. Flash Point: 166.9 °C
    4. Appearance: /
    5. Density: 1.338 g/cm3
    6. Refractive Index: N/A
    7. Storage Temp.: Sealed in dry,Room Temperature
    8. Solubility: N/A
    9. CAS DataBase Reference: N-BOC-3-AMINO-4-CHLOROBENZOIC ACID(CAS DataBase Reference)
    10. NIST Chemistry Reference: N-BOC-3-AMINO-4-CHLOROBENZOIC ACID(160450-12-4)
    11. EPA Substance Registry System: N-BOC-3-AMINO-4-CHLOROBENZOIC ACID(160450-12-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 160450-12-4(Hazardous Substances Data)

160450-12-4 Usage

Uses

Used in Pharmaceutical Synthesis:
N-BOC-3-AMINO-4-CHLOROBENZOIC ACID is used as a key building block for the synthesis of various pharmaceuticals. Its presence in the molecular structure allows for the development of new drugs with specific therapeutic properties.
Used in Agrochemical Production:
In the agrochemical industry, N-BOC-3-AMINO-4-CHLOROBENZOIC ACID is utilized as a precursor in the production of various agrochemicals, contributing to the development of effective crop protection agents.
Used in Organic Chemistry Reactions:
N-BOC-3-AMINO-4-CHLOROBENZOIC ACID is employed as a reagent in organic chemistry, particularly for the formation of amide bonds. Its use facilitates the synthesis of complex organic molecules and contributes to the advancement of organic chemistry research.
It is important to handle N-BOC-3-AMINO-4-CHLOROBENZOIC ACID with proper safety precautions due to its potential harmful effects if ingested or inhaled.

Check Digit Verification of cas no

The CAS Registry Mumber 160450-12-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,0,4,5 and 0 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 160450-12:
(8*1)+(7*6)+(6*0)+(5*4)+(4*5)+(3*0)+(2*1)+(1*2)=94
94 % 10 = 4
So 160450-12-4 is a valid CAS Registry Number.

160450-12-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-chloro-3-[(2-methylpropan-2-yl)oxycarbonylamino]benzoic acid

1.2 Other means of identification

Product number -
Other names N-Boc-3-amino-4-chlorobenzoic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:160450-12-4 SDS

160450-12-4Upstream product

160450-12-4Downstream Products

160450-12-4Relevant articles and documents

Design and synthesis of α-ketoamides as cathepsin s inhibitors with potential applications against tumor invasion and angiogenesis

Chen, Jo-Chun,Uang, Biing-Jiun,Lyu, Ping-Chiang,Chang, Jang-Yang,Liu, Ko-Jiunn,Kuo, Ching-Chuan,Hsieh, Hsing-Pang,Wang, Hsin-Chieh,Cheng, Chao-Sheng,Chang, Yi-Hsun,Chang, Margaret Dah-Tsyr,Chang, Wun-Shaing Wayne,Lin, Chun-Cheng

scheme or table, p. 4545 - 4549 (2010/08/19)

A series of small molecules bearing an α-ketoamide warhead were synthesized and evaluated for their ability to inhibit cathepsin S, a key proteolytic enzyme upregulated in many cancers during tumor progression and metastasis. Most of the synthetic compounds were noncytotoxic, but several robustly inhibited cathepsin S (IC50 10 nM) and potently suppressed cell migration, invasion, and capillary tube formation. These results highlight the potential of α-ketoamide therapy for preventing or delaying cancer spread.

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