An efficient and scalable synthesis of arabinosylguanine and 2′-deoxy-2′-fluoro-guanosine
An efficient conversion from commercially available 2,6-diaminopurine-2′,3′,5′-tri-O-benzyl arabinoside to arabinosylguanine and its further transformation to 2′-deoxy-2′-fluoro-guanosine is outlined. This process has been used to produce more than one hundred grams of final product. Copyright
Ross, Bruce S.,Springer, Robert H.,Sprankle, Kelly G.,Vasquez, Guillermo
p. 1645 - 1647
(2007/10/03)
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