- Substituted 1,3-oxathiolanes and substituted 1,3-dithiolanes with antiviral properties
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This invention relates to novel substituted 1,3-oxathiolanes and substituted 1,3-dithiolanes or pharmaceutically acceptable salts and esters thereof, of the formula: STR1 wherein X is S, S=O, or SO2 ; Y is O, S, S=O, or SO2 ; R1
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- Synthesis of Optically Active 2',3'-Dideoxy-3'-oxa-4'-thio-ribonucleoside Analogues by Transposition of a Leaving Group on Chiral Oxathiolanes via a Reductive-oxidative Process
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The synthesis of chiral nucleoside analogues with a unique structural feature is reported.The strategy is based on a reductive-oxidative process to complete the transposition of the leaving group in chiral oxathiolanes with known configuration.
- Wang, Wei,Jin, Haolun,Mansour, Tarek S.
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p. 4739 - 4742
(2007/10/02)
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