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(S)-3-(benzylamino)-2-(benzyloxycarbonylamino)propanoic acid, also known as Boc-Glu(OBzl)-OMe, is a chemical compound derived from glutamic acid with two benzyl groups. It is a proline-containing dipeptide derivative that has potential applications in peptide synthesis and the development of peptidomimetics, synthetic compounds that mimic the structure and function of peptides. Its unique structure and properties make it a promising candidate for further research and development in various fields of chemistry and medicine, including potential therapeutic applications in the treatment of neurological disorders and other diseases.

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  • 160885-24-5 Structure
  • Basic information

    1. Product Name: (S)-3-(benzylamino)-2-(benzyloxycarbonylamino)propanoic acid
    2. Synonyms: (S)-3-(benzylamino)-2-(benzyloxycarbonylamino)propanoic acid;(2S)-3-(benzylamino)-2-(benzyloxycarbonylamino)propanoic acid
    3. CAS NO:160885-24-5
    4. Molecular Formula: C18H20N2O4
    5. Molecular Weight: 328.3624
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 160885-24-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 553.795°C at 760 mmHg
    3. Flash Point: 288.725°C
    4. Appearance: /
    5. Density: 1.239g/cm3
    6. Vapor Pressure: 0mmHg at 25°C
    7. Refractive Index: 1.589
    8. Storage Temp.: 2-8°C
    9. Solubility: N/A
    10. PKA: 2.86±0.18(Predicted)
    11. CAS DataBase Reference: (S)-3-(benzylamino)-2-(benzyloxycarbonylamino)propanoic acid(CAS DataBase Reference)
    12. NIST Chemistry Reference: (S)-3-(benzylamino)-2-(benzyloxycarbonylamino)propanoic acid(160885-24-5)
    13. EPA Substance Registry System: (S)-3-(benzylamino)-2-(benzyloxycarbonylamino)propanoic acid(160885-24-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 160885-24-5(Hazardous Substances Data)

160885-24-5 Usage

Uses

Used in Peptide Synthesis:
(S)-3-(benzylamino)-2-(benzyloxycarbonylamino)propanoic acid is used as a building block in peptide synthesis for the creation of novel peptides with specific functions and properties. Its incorporation into peptide sequences allows for the development of bioactive peptides with potential applications in various industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (S)-3-(benzylamino)-2-(benzyloxycarbonylamino)propanoic acid is used as a key intermediate in the synthesis of peptidomimetics. These synthetic compounds have the potential to exhibit improved pharmacokinetic properties, such as enhanced stability, bioavailability, and reduced immunogenicity compared to natural peptides. Peptidomimetics can be designed to target specific biological receptors or enzymes, making them valuable for the development of new drugs for various therapeutic areas, including neurological disorders and other diseases.
Used in Research and Development:
(S)-3-(benzylamino)-2-(benzyloxycarbonylamino)propanoic acid is used as a research tool in the field of chemistry and medicine. Its unique structure and properties make it an interesting compound for studying the interactions between peptides and their target molecules, as well as for exploring new methods of peptide synthesis and modification. This research can contribute to the advancement of our understanding of peptide-based therapeutics and the development of new drugs with improved efficacy and safety profiles.

Check Digit Verification of cas no

The CAS Registry Mumber 160885-24-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,0,8,8 and 5 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 160885-24:
(8*1)+(7*6)+(6*0)+(5*8)+(4*8)+(3*5)+(2*2)+(1*4)=145
145 % 10 = 5
So 160885-24-5 is a valid CAS Registry Number.
InChI:InChI=1/C18H20N2O4/c21-17(22)16(12-19-11-14-7-3-1-4-8-14)20-18(23)24-13-15-9-5-2-6-10-15/h1-10,16,19H,11-13H2,(H,20,23)(H,21,22)/t16-/m0/s1

160885-24-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S)-3-(benzylamino)-2-(phenylmethoxycarbonylamino)propanoic acid

1.2 Other means of identification

Product number -
Other names (S)-3-(benzylamino)-2-(benzyloxycarbonylamino)propanoic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:160885-24-5 SDS

160885-24-5Downstream Products

160885-24-5Relevant articles and documents

Reaction of Trimethylsilylamines with N-Cbz-L-Serine-β-Lactone: A Convenient Route to Optically Pure β-Amino-L-alanine Derivatives

Ratemi, Elaref S.,Vederas, John C.

, p. 7605 - 7608 (2007/10/02)

Trimethylsilylamines, Me3Si-NR2, react with N-Cbz-L-serine-β-lactone in acetonitrile primarily by alkyl oxygen cleavage of the lactone ring to give optically pure N-Cbz-β-amino-L-alanine derivatives in good yields.Use of halogenated sovents such as chloro

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