An efficient one-pot synthesis of aryl-substituted 1-(thiazol-2-yl)-1H- pyrazole-3-carboxylates via a hantzsch synthesis-knorr reaction sequence
The treatment of α-bromoalkyl aryl ketones and 2-(propan-2-ylidene) hydrazine carbothioamide afforded 4-aryl-2-(2-(propan-2-ylidene)hydrazinyl) thiazoles via a Hantzsch-thiazole synthesis, which reacted with 4-aryl-2,4-diketoesters via a sequential Knorr-