One-pot, three-component synthesis of pyranocoumarins containing an aroyl group
An expeditious method to prepare pyranocoumarins containing an aroyl group by the three-component reaction of 4-hydroxycoumarin with arylglyoxals and malononitrile is described. The reaction is efficiently catalyzed by Mohr's salt, and the products were o
One-pot synthesis of novel pyrano-fused coumarins catalyzed by zinc oxide nanoparticles
A new class of pyrano[3,2-c]coumarins containing an aryloylgroup was synthesized via the three-component reactions of 4-hydroxycoumarin with arylglyoxals and malononitrile. The reactions are efficiently catalyzed by zinc oxide nanoparticles as powerful and recyclable catalyst. The green chemistry principles were also considered and the present method has some advantages, such as simplicity, low catalyst loading, and high yields.
Synthesis of new 4-aroyl-pyrano[c]chromenes via a one-pot, three-component reaction based on aryl glyoxals
A new library of pyrano[c]chromenes containing an aroyl group has been synthesized by a novel multicomponent process involving the reaction of various aryl glyoxals with 4-hydroxycoumarin and malononitrile. The reactions were catalyzed efficiently by ammonium dihydrogen phosphate to yield the desired products in good to excellent yields.
A new three-component coupling reaction of aryl glyoxal, malononitrile, and 4-hydroxy coumarin catalysed by recyclable TiO2 nanoparticles
Aryl glyoxals reacted with malononitrile and 4-hydroxycoumarin in the presence of a catalytic amount of TiO2 nanoparticles to give a hitherto unknown family of pyranochromenes in up to 80% yield. This new three-component reaction yielded some novel pyrano[3,2-c]chromene-5-ones containing an aroyl substituent. Using a recyclable and safe catalyst along with a green solvent system made the process eco-friendly and economic.