161489-04-9

Basic information

• Product Name: Pyrimidine, 2-ethynyl-4-methoxy- (9CI)
• Synonyms: Pyrimidine, 2-ethynyl-4-methoxy- (9CI);2-Ethynyl-4-methoxypyrimidine
• CAS NO: 161489-04-9
• Molecular Formula: C₇H₆N₂O
• Molecular Weight: 134.13534
• Product Categories: PYRIMIDINE
• Mol File: 161489-04-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Pyrimidine, 2-ethynyl-4-methoxy- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrimidine, 2-ethynyl-4-methoxy- (9CI)(161489-04-9)
• EPA Substance Registry System: Pyrimidine, 2-ethynyl-4-methoxy- (9CI)(161489-04-9)

Safety Data

• Hazardous Substances Data: 161489-04-9(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
Pyrimidine, 2-ethynyl-4-methoxy(9CI) is used as a building block in organic synthesis for the creation of more complex organic molecules. Its unique structure and reactivity make it a valuable component in the synthesis of a wide range of compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, Pyrimidine, 2-ethynyl-4-methoxy(9CI) is used as a key intermediate in the development of novel pharmaceutical agents. Its potential biological activity makes it a promising candidate for the creation of new drugs with various therapeutic applications.
Used in Material Science:
Pyrimidine, 2-ethynyl-4-methoxy(9CI) may also find applications in material science, where its properties could be harnessed to develop new materials with specific characteristics, such as improved stability or reactivity.
Used in Agrochemicals:
In the agrochemical industry, Pyrimidine, 2-ethynyl-4-methoxy(9CI) could be utilized in the development of new agrochemical products, such as pesticides or herbicides, that could offer enhanced efficacy or reduced environmental impact.
Used in Industrial Processes:
Pyrimidine, 2-ethynyl-4-methoxy(9CI)'s reactivity and properties may also make it a valuable component in various industrial processes, where it could be used to improve the efficiency or effectiveness of certain manufacturing or production methods.

Upstream product

• 22536-63-6 2-chloro-4-methoxypyrimidine 
• 161489-00-5 4-Methoxy-2-<(trimethylsilyl)ethynyl>pyrimidine 

Downstream Products

• 219915-22-7 4,4'-dimethoxy-2,5'-(1,4-phenylenedi-2,1-ethynediyl)bispyrimidine 
• 219915-21-6 2-<(4-bromophenyl)ethynyl>-4-methoxypyrimidine 

Relevant articles and documents

PYRAZOLE DERIVATIVES AS JAK INHIBITORS

New pyrazole derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Janus Kinases (JAK).

Pyrazole derivatives as jak inhibitors

New pyrazole derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Janus Kinases (JAK).

Use of Hydrogen Bonds To Control Molecular Aggregation. Behavior of Dipyridones and Pyridone-Pyrimidones Designed To Form Cyclic Triplexes

The tendency of 2-pyridones and related heterocycles to form cyclic hydrogen-bonded dimers allows them to be used as sticky sites that induce molecules in which they are incorporated to associate in particular ways.Compound 7, which is constructed from pyridone and pyrimidone subunits linked to a rigid linear acetylenic spacer, incorporates an array of hydrogen-bonding sites designed to favor the formation of a cyclic triplex.Pyridone-pyrimidone 7 was synthesized and the structure of its DMSO solvate was determined by X-ray crystallography.Aggregation does not produce a cyclic triplex but rather gives chains in which adjacent molecules of compound 7 are linked by single hydrogen bonds.