Inhibitors of HIV-1 proteinase containing 2-heterosubstituted 4-amino-3- hydroxy-5-phenylpentanoic acid: Synthesis, enzyme inhibition, and antiviral activity
A convenient procedure for the synthesis of 2-heterosubstituted statine derivatives as novel building blocks in HIV-protease inhibitors has been developed. The synthesis starts with protected L-phenylalaninols, which were converted to γ-amino α,β-unsatura
Get Best Price for161510-40-3benzyl [(2S)-1-{[(2S,3R,4R)-5-{[(2S)-1-(benzylamino)-3-methyl-1-oxobutan-2-yl]amino}-4-(cyclohexylamino)-3-hydroxy-5-oxo-1-phenylpentan-2-yl]amino}-3-methyl-1-oxobutan-2-yl]carbamate (non-preferred name)