The present invention relates to compounds of the formula STR1 wherein R1 is an acyl group derived from a carboxylic acid, hydrogen, or an amino protecting group; R2 is hydrogen, hydroxy, lower alkyl-Qp -, cycloalkyl, lowe
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(2008/06/13)
Synthesis and structure-activity relationship of (lactamylvinyl)cephalosporins exhibiting activity against staphylococci, pneumococci, and enterococci
The synthesis and structure-activity relationships of a new class of vinylcephalosporins substituted with a lactamyl residue (1) are described. These compounds show excellent activity against enterococci and retain the broad spectrum activity of third-gen
Heinze-Krauss, Ingrid,Angehrn, Peter,Guerry, Philippe,Hebeisen, Paul,Hubschwerlen, Christian,Kompis, Ivan,Page, Malcolm G. P.,Richter, Hans G. F.,Runtz, Valérie,Stalder, Henri,Weiss, Urs,Wei, Chung-Chen
Get Best Price for161672-76-0(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(hydroxyimino)acetyl]amino}-8-oxo-3-{(E)-[2-oxo-1-(2,2,2-trifluoroethyl)pyrrolidin-3-ylidene]methyl}-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid