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1,3-Thiazol-5-ylmethylamine, a chemical compound with the molecular formula C4H6N2S, is a derivative of thiazole that features an amine functional group. It has been recognized as a promising building block for the synthesis of a variety of pharmaceuticals and organic compounds. Its potential applications span across the fields of medicinal chemistry, agrochemicals, and material science, with particular interest in its development as an antifungal and antibacterial agent.

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  • 161805-76-1 Structure
  • Basic information

    1. Product Name: 1,3-THIAZOL-5-YLMETHYLAMINE
    2. Synonyms: 1,3-THIAZOL-5-YLMETHYLAMINE;5-THIAZOLEMETHANAMINE;ALINDA 274;C-THIAZOL-5-YL-METHYLAMINE;OTAVA-BB 1087987;THIAZOL-5-YL-METHYLAMINE;1,3-Thiazol-5-ylmethylamine hydrobromide;5-(Aminomethyl)-1,3-thiazole 95+%
    3. CAS NO:161805-76-1
    4. Molecular Formula: C4H6N2S
    5. Molecular Weight: 114.17
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 161805-76-1.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 221℃
    3. Flash Point: 87℃
    4. Appearance: /
    5. Density: 1.239
    6. Vapor Pressure: 0.112mmHg at 25°C
    7. Refractive Index: 1.592
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. PKA: 8.24±0.29(Predicted)
    11. CAS DataBase Reference: 1,3-THIAZOL-5-YLMETHYLAMINE(CAS DataBase Reference)
    12. NIST Chemistry Reference: 1,3-THIAZOL-5-YLMETHYLAMINE(161805-76-1)
    13. EPA Substance Registry System: 1,3-THIAZOL-5-YLMETHYLAMINE(161805-76-1)
  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 161805-76-1(Hazardous Substances Data)

161805-76-1 Usage

Uses

Used in Pharmaceutical Industry:
1,3-Thiazol-5-ylmethylamine is used as a key intermediate in the synthesis of new drugs for its potential antifungal and antibacterial properties. It contributes to the development of medications aimed at treating infections caused by fungi and bacteria, enhancing the arsenal of treatments available to combat resistant strains.
Used in Agrochemical Industry:
In the agrochemical field, 1,3-Thiazol-5-ylmethylamine is utilized as a component in the creation of pesticides and fungicides. Its incorporation aids in the protection of crops from fungal and bacterial diseases, thereby improving agricultural yields and food security.
Used in Material Science:
1,3-Thiazol-5-ylmethylamine is employed in the synthesis of new materials with tailored chemical and physical properties. Its unique structure allows for the development of materials with specific applications in various industries, such as in the creation of advanced polymers or other functional materials with targeted properties.
Overall, 1,3-Thiazol-5-ylmethylamine's versatility and potential across different sectors highlight its importance in the ongoing pursuit of innovative solutions in healthcare, agriculture, and material development.

Check Digit Verification of cas no

The CAS Registry Mumber 161805-76-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,1,8,0 and 5 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 161805-76:
(8*1)+(7*6)+(6*1)+(5*8)+(4*0)+(3*5)+(2*7)+(1*6)=131
131 % 10 = 1
So 161805-76-1 is a valid CAS Registry Number.
InChI:InChI=1/C4H6N2S/c5-1-4-2-6-3-7-4/h2-3H,1,5H2

161805-76-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,3-thiazol-5-ylmethanamine

1.2 Other means of identification

Product number -
Other names 1,3-thiazol-5-ylmethylamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:161805-76-1 SDS

161805-76-1Upstream product

161805-76-1Downstream Products

161805-76-1Relevant articles and documents

Design and synthesis of new potent C2-symmetric HIV-1 protease inhibitors. Use of L-mannaric acid as a peptidomimetic scaffold

Alterman, Mathias,Bj?rsne, Magnus,Mühlman, Anna,Classon, Bj?rn,Kvarnstr?m, Ingemar,Danielson, Helena,Markgren, Per-Olof,Nillroth, Ulrika,Unge, Torsten,Hallberg, Anders,Samuelsson, Bertil

, p. 3782 - 3792 (2007/10/03)

A study on the use of derivatized carbohydrates as C2-symmetric HIV-1 protease inhibitors has been undertaken. L-Mannaric acid (6) was bis-O- benzylated at C-2 and C-5 and subsequently coupled with amino acids and amines to give C2-s

Quinazoline derivatives possessing anti-tumor activity

-

, (2008/06/13)

The invention relates to quinazoline derivatives, or pharmaceutically-acceptable salts thereof, which possess anti-tumor activity; to processes for their manufacture; and to pharmaceutical compositions containing them. The invention provides a quinazoline of the formula: STR1 wherein R1 is hydrogen or amino, or alkyl or alkoxy each of up to 6 carbon atoms; or R1 is substituted alkyl or alkoxy each of up to 3 carbon atoms; R2 is hydrogen, alkyl, alkenyl, alkynyl, hydroxyalkyl, halogenoalkyl or cyanoalkyl each of up to 6 carbon atoms; Ar is phenylene or heterocyclene; L is a group of the formula --CO.NH--, --NH.CO--, --CO.NR3 --, --NR3. CO--, --CH=CH--, --CH2 O--, --OCH2, --CH2 S--, --SCH2 --, --CO.CH2 --, --CH2.CO-- or --CO.O--, wherein R3 is alkyl of up to 6 carbon atoms; and Y is aryl or heteroaryl or a hydrogenated derivative thereof: or Y is a group of the formula --A--Y1 in which A is alkylene, cycloalkylene, alkenylene or alkynylene each of up to 6 carbon atoms and Y1 is aryl or heteroaryl or a hydrogenated derivative thereof; or a pharmaceutically-acceptable salt thereof.

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