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5-BROMOURIDINE 5'-TRIPHOSPHATE SODIUM, also known as 5-BrUTP, is a modified nucleotide that plays a crucial role in the field of molecular biology and biochemistry. It is a derivative of uridine triphosphate (UTP) with a bromine atom substituted at the 5-position of the uracil base. This modification allows for the detection and analysis of RNA synthesis and transcription processes.

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  • 161848-60-8 Structure
  • Basic information

    1. Product Name: 5-BROMOURIDINE 5'-TRIPHOSPHATE SODIUM
    2. Synonyms: 5-Bromouridine 5'-triphosphoric acid;5-BromoUTP;5-BROMOURIDINE 5'-TRIPHOSPHATE SODIUM;BrUTP [5-Bromouridine 5'-triphosphate] *10 mM in TE buffer* *CAS 161848-60-8*
    3. CAS NO:161848-60-8
    4. Molecular Formula: C9H10BrN2Na4O15P3
    5. Molecular Weight: 650.964463
    6. EINECS: N/A
    7. Product Categories: Biochemicals and Reagents;Nucleosides, Nucleotides, Oligonucleotides;Nucleotide Analogs
    8. Mol File: 161848-60-8.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: −20°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 5-BROMOURIDINE 5'-TRIPHOSPHATE SODIUM(CAS DataBase Reference)
    10. NIST Chemistry Reference: 5-BROMOURIDINE 5'-TRIPHOSPHATE SODIUM(161848-60-8)
    11. EPA Substance Registry System: 5-BROMOURIDINE 5'-TRIPHOSPHATE SODIUM(161848-60-8)
  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: 36/37/38
    3. Safety Statements: 22-26-36
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 161848-60-8(Hazardous Substances Data)

161848-60-8 Usage

Uses

Used in Molecular Biology and Biochemistry:
5-BROMOURIDINE 5'-TRIPHOSPHATE SODIUM is used as a labeling agent for the detection and analysis of ribonucleic acid (RNA) synthesis and transcription. It is incorporated into newly synthesized RNA during transcription, allowing for the identification and quantification of RNA molecules.
Used in Research Applications:
In the field of research, 5-BROMOURIDINE 5'-TRIPHOSPHATE SODIUM is used as a tool for studying gene expression, RNA processing, and other cellular processes involving RNA. It can be employed in various experimental techniques, such as in situ hybridization, Northern blotting, and RNA sequencing, to provide valuable insights into the regulation and function of specific genes and RNA molecules.
Used in Diagnostic Applications:
5-BROMOURIDINE 5'-TRIPHOSPHATE SODIUM can be utilized in the development of diagnostic tests for various diseases, particularly those involving alterations in gene expression or RNA processing. By incorporating this modified nucleotide into RNA during transcription, researchers can detect and monitor the expression of specific genes or RNA molecules associated with disease states, potentially leading to the development of novel diagnostic tools and therapies.
Used in Drug Discovery and Development:
In the pharmaceutical industry, 5-BROMOURIDINE 5'-TRIPHOSPHATE SODIUM can be employed in the screening and identification of potential drug targets related to RNA synthesis and processing. By studying the effects of various compounds on the incorporation of 5-BrUTP into RNA, researchers can gain a better understanding of the molecular mechanisms underlying specific diseases and identify potential therapeutic agents that modulate RNA synthesis and transcription.

Check Digit Verification of cas no

The CAS Registry Mumber 161848-60-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,1,8,4 and 8 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 161848-60:
(8*1)+(7*6)+(6*1)+(5*8)+(4*4)+(3*8)+(2*6)+(1*0)=148
148 % 10 = 8
So 161848-60-8 is a valid CAS Registry Number.

161848-60-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name Disodium 5-bromo-5'-O-({[hydroxy({hydroxy[(hydroxyphosphinato)oxy ]phosphoryl}oxy)phosphoryl]oxy}phosphinato)uridine

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:161848-60-8 SDS

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