cas 1623791-99-0, Azido-PEG8-t-butyl ester | Articles data ｜lookchem

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1623791-99-0

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DIRECTED CONJUGATION TECHNOLOGIES
Among other things, the present disclosure provides technologies for site-directed conjugation of various moieties of interest to target agents. In some embodiments, the present disclosure utilizes target binding moieties to provide high conjugation efficiency and selectivity. In some embodiments, provided technologies are useful for preparing antibody conjugates.
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Paragraph 0579; 0580

(2021/05/29)

Efficient synthesis of small-sized phosphonated dendrons: Potential organic coatings of iron oxide nanoparticles
We report herein the synthesis of biocompatible small-sized phosphonated monomers and dendrons used as functional coatings of metal oxide nanoparticles, more specifically superparamagnetic iron oxides (SPIOs) for magnetic resonance imaging (MRI) and therapy through hyperthermia. The molecules were engineered to modulate their size, their hydrophilic and/or biocompatible character (poly(amido)amine versus oligoethyleneglycol), the number of anchoring phosphonate groups (monophosphonate versus phosphonic tweezers) and the number of peripheral functional groups for further grafting of dyes or specific vectors. Such a library of hydrophilic phosphonic acids opens new possibilities for the investigation of dendronized nanohybrids as theranostics.
Garofalo, Antonio,Parat, Audrey,Bordeianu, Catalina,Ghobril, Cynthia,Kueny-Stotz, Marie,Walter, Aurlie,Jouhannaud, Julien,Begin-Colin, Sylvie,Felder-Flesch, Delphine
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p. 5226 - 5239
(2014/12/10)

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1214319-92-2
27-azido-4,7,10,13,16,19,22,25-octaoxaheptacosanoic acid

Chemical Properties

Solubility:Soluble in Water, DMSO, DCM, DMF

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