1623792-00-6

Basic information

• Product Name: Bromo-PEG8-t-butyl ester
• Synonyms: Bromo-PEG8-t-butyl ester;Bromo-PEG9-t-butyl ester;Br-PEG8-t-butyl ester;Br-PEG8-CH2CH2COOtBu
• CAS NO: 1623792-00-6
• Molecular Formula: C23H45BrO10
• Molecular Weight: 561.5014
• Mol File: 1623792-00-6.mol

Chemical Properties

• Boiling Point: 557.0±45.0 °C(Predicted)
• Appearance: /
• Density: 1.180±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Bromo-PEG8-t-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Bromo-PEG8-t-butyl ester(1623792-00-6)
• EPA Substance Registry System: Bromo-PEG8-t-butyl ester(1623792-00-6)

Safety Data

• Hazardous Substances Data: 1623792-00-6(Hazardous Substances Data)

Usage

Uses

Used in Bioconjugation and Drug Synthesis:
Bromo-PEG8-t-butyl ester is used as a bioconjugation agent for the attachment of biomolecules to other molecules or surfaces. The bromide group facilitates nucleophilic substitution reactions, allowing for the efficient coupling of biomolecules such as proteins, peptides, or nucleic acids. This property makes it a valuable tool in the development of drugs, diagnostics, and other bioactive compounds.
Used in Drug Delivery Systems:
In the pharmaceutical industry, Bromo-PEG8-t-butyl ester is used as a component in drug delivery systems. The hydrophilic PEG spacer improves the solubility and stability of drug molecules, while the t-butyl protected carboxyl group can be deprotected under specific conditions to release the active drug. This controlled release mechanism can enhance the efficacy and bioavailability of the drug, as well as reduce side effects.
Used in Surface Modification:
Bromo-PEG8-t-butyl ester is used as a surface modification agent in various applications, such as in the creation of self-assembled monolayers (SAMs) on solid surfaces. The PEG linker provides a hydrophilic barrier, which can reduce non-specific adsorption of biomolecules and improve the performance of sensors or other devices. Additionally, the bromide group can be used to attach other functional groups or molecules to the surface, tailoring its properties for specific applications.
Used in Polymer Science:
In polymer science, Bromo-PEG8-t-butyl ester can be used as a building block for the synthesis of complex polymer structures. The bromide group can be used to initiate polymerization reactions, while the PEG linker and t-butyl protected carboxyl group can be incorporated into the polymer backbone to provide specific properties, such as enhanced solubility, biocompatibility, or controlled degradation.
Overall, Bromo-PEG8-t-butyl ester is a versatile molecule with a wide range of applications in various industries, including pharmaceuticals, biotechnology, materials science, and surface modification. Its unique combination of properties, such as the hydrophilic PEG spacer, the reactive bromide group, and the t-butyl protected carboxyl group, make it a valuable tool for the development of new drugs, diagnostics, and other bioactive compounds.