Welcome to LookChem.com Sign In|Join Free

CAS

  • or

16264-67-8

4,5,6,7-Tetrafluoroindole, with the CAS number 16264-67-8, is an organic compound characterized by the presence of four fluorine atoms at positions 4, 5, 6, and 7 on the indole ring. This unique structure endows it with specific properties that make it suitable for various applications in different industries.

16264-67-8 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 16264-67-8 Structure

  • Basic information

    1. Product Name: 4,5,6,7-TETRAFLUOROINDOLE
    2. Synonyms: 4,5,6,7-TETRAFLUORO-1H-INDOLE;4,5,6,7-TETRAFLUOROINDOLE;1H-Indole, 4,5,6,7-tetrafluoro-;4,5,6,7-Tetrafluoro-1H-indole98%
    3. CAS NO:16264-67-8
    4. Molecular Formula: C8H3F4N
    5. Molecular Weight: 189.11
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 16264-67-8.mol

  • Chemical Properties

    1. Melting Point: 90-91
    2. Boiling Point: 258.6°Cat760mmHg
    3. Flash Point: 110.2°C
    4. Appearance: /
    5. Density: 1.593g/cm3
    6. Vapor Pressure: 0.022mmHg at 25°C
    7. Refractive Index: 1.562
    8. Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
    9. Solubility: N/A
    10. PKA: 13.51±0.30(Predicted)
    11. CAS DataBase Reference: 4,5,6,7-TETRAFLUOROINDOLE(CAS DataBase Reference)
    12. NIST Chemistry Reference: 4,5,6,7-TETRAFLUOROINDOLE(16264-67-8)
    13. EPA Substance Registry System: 4,5,6,7-TETRAFLUOROINDOLE(16264-67-8)

  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: 36/37/38
    3. Safety Statements: 26-36
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 16264-67-8(Hazardous Substances Data)

16264-67-8 Usage

Uses

Used in Chemical Industry:
4,5,6,7-Tetrafluoroindole is used as an activator for metallocene-catalyzed polymerization. Metallocene catalysts are a class of transition metal complexes that are widely used in the polymer industry for the production of polyolefins, such as polyethylene and polypropylene. The activation provided by 4,5,6,7-tetrafluoroindole enhances the efficiency and selectivity of the polymerization process, leading to improved polymer properties and performance.

Check Digit Verification of cas no

The CAS Registry Mumber 16264-67-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,2,6 and 4 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 16264-67:
(7*1)+(6*6)+(5*2)+(4*6)+(3*4)+(2*6)+(1*7)=108
108 % 10 = 8
So 16264-67-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H3F4N/c9-4-3-1-2-13-8(3)7(12)6(11)5(4)10/h1-2,13H

16264-67-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 4,5,6,7-Tetrafluoroindole

1.2 Other means of identification

Product number -
Other names 4,5,6,7-tetrafluoro-1H-indole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:16264-67-8 SDS

16264-67-8Relevant articles and documents

PARTIALLY FLUORINATED HETEROCYCLIC COMPOUNDS. PART 19. THE FORMATION OF FISCHER INDOLE PRODUCTS FROM A SERIES OF HYDRAZONES DERIVED FROM PENTAFLUOROPHENYLHYDRAZINE AND 1,3,4,5,6,7,8-HEPTAFLUORO-2-NAPHTHYLHYDRAZINE. THE SURPRISING LOSS OF o-FLUORINE

Benke, Frank D.,Brooke, Gerald M.

, p. 77 - 86 (1984)

The pentafluorophenyl and 1,3,4,5,6,7,8-heptafluoro-2-naphthylhydrazones of a variety of aldehydes and ketones give 4,5,6,7-tetrafluoroindole and 4,5,6,7,8,9-hexafluorobenzindole derivatives when heated under reflux in tetralin.These products are typic

The synthesis of 7,8,9,10-Tetrafluoroellipticine

James Gruver,Onyango, Evans O.,Gribble, Gordon W.

, p. 144 - 152 (2018/07/05)

We have synthesized a novel ellipticine analogue, 7,8,9,10-Tetrafluoroellipticine, in nine steps from hexafluorobenzene and ethyl cyanoacetate, via 1-(phenysulfonyl)-4,5,6,7-Tetrafluoroindole. The key step is lithiation of the indole and subsequent coupling with 3,4-pyridinedicarboxylic acid anhydride to afford a ketolactam. Reaction of the lactam with methyllithium followed by reduction with sodium borohydride yields 7,8,9,10-Tetrafluoroellipticine. formula presented.

Synthesis of indoles with a polyfluorinated benzene ring

Politanskaya, Larisa V.,Chuikov, Igor P.,Shteingarts, Vitalij D.

, p. 8477 - 8486 (2013/09/02)

A two-step sequence consisting of a Sonogashira coupling of polyfluorinated 2-iodoanilines with terminal alkynes, followed by a KOH promoted cyclization of the 2-alkynylanilines thus formed, has been developed as a one-pot synthesis of 2-R-indoles (R=n-Bu

Polyfluoroaralkylamines: an improved synthesis of 4,5,6,7-tetrafluoroindole

Filler, Robert,Chen, Wei,Woods, Sarah M.

, p. 95 - 100 (2007/10/02)

Tetrafluoroindole (5), a precursor for potential biologically-active compounds, was prepared previously in a four-step synthesis from C6F6.However, catalytic reduction of pentafluorophenylacetonitrile (2) to 2-pentafluorophenylethyl amine (3) is accompanied by a significant amount of a secondary amine, which, like 3, undergoes cyclization to an indoline and subsequent dehydrogenation to a new indole 8.The side-reaction in the reduction of 2 to 3 is obviated by the use of LiAlH4/AlCl3 (1:1).The final aromatization to yield 5 is vastly improved by replacing MnO2 with DDQ. - Keywords: Polyfluoroaralkylamines; Synthesis; Tetrafluoroindole; NMR spectroscopy; IR spectroscopy

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 16264-67-8