162707-52-0Relevant articles and documents
Novel N-chloroheterocyclic antimicrobials
Francavilla, Charles,Turtle, Eric D.,Kim, Bum,O'Mahony, Donogh J.R.,Shiau, Timothy P.,Low, Eddy,Alvarez, Nichole J.,Celeri, Chris E.,D'Lima, Louisa,Friedman, Lisa C.,Ruado, Francis S.,Xu, Ping,Zuck, Meghan E.,Anderson, Mark B.,Najafi, Ramin,Jain, Rakesh K.
scheme or table, p. 3029 - 3033 (2011/06/24)
Antimicrobial compounds with broad-spectrum activity and minimal potential for antibiotic resistance are urgently needed. Toward this end, we prepared and investigated a novel series of N-chloroheterocycles. Of the compounds examined, the N-chloroamine series were found superior over N-chloroamide series in regards to exhibiting high antimicrobial activity, low cytotoxicity, and long-term aqueous stability.
ANTIMICROBIAL OXAZOLIDINONE, HYDANTOIN AND IMIDAZOLIDINONE COMPOSITIONS
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Page/Page column 64, (2010/06/11)
The present application relates to N-chlorinated oxazolidinone, hydantoin and imidazolidinone compounds of Formula (I): or pharmaceutically acceptable salts thereof, and associated compositions and methods of use as antimicrobial agents.