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N-(Piperidin-4-Yl)-6-(2,2,2-Trifluoroethyl)Thieno[2,3-D]Pyrimidin-4-Amine is a chemical compound that belongs to the thieno[2,3-d]pyrimidine class. It features a piperidine ring attached to a thieno[2,3-d]pyrimidine moiety, with a 2,2,2-trifluoroethyl group at position 6 of the thieno[2,3-d]pyrimidine ring. This unique structure may confer potential pharmacological applications, making it a promising candidate for the development of new drugs targeting specific biological pathways or receptors. It also holds potential for use in chemical research and development.

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  • N-(Piperidin-4-Yl)-6-(2,2,2-Trifluoroethyl)Thieno[2,3-D]Pyrimidin-4-Amine

    Cas No: 1628317-93-0

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  • N-(Piperidin-4-yl)-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-amine

    Cas No: 1628317-93-0

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  • 1628317-93-0 Structure
  • Basic information

    1. Product Name: N-(Piperidin-4-Yl)-6-(2,2,2-Trifluoroethyl)Thieno[2,3-D]Pyrimidin-4-Amine
    2. Synonyms: N-(Piperidin-4-Yl)-6-(2,2,2-Trifluoroethyl)Thieno[2,3-D]Pyrimidin-4-Amine;N-4-Piperidinyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-amine
    3. CAS NO:1628317-93-0
    4. Molecular Formula: C13H15F3N4S
    5. Molecular Weight: 316.35
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1628317-93-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 435.8±45.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.395±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 9.93±0.10(Predicted)
    10. CAS DataBase Reference: N-(Piperidin-4-Yl)-6-(2,2,2-Trifluoroethyl)Thieno[2,3-D]Pyrimidin-4-Amine(CAS DataBase Reference)
    11. NIST Chemistry Reference: N-(Piperidin-4-Yl)-6-(2,2,2-Trifluoroethyl)Thieno[2,3-D]Pyrimidin-4-Amine(1628317-93-0)
    12. EPA Substance Registry System: N-(Piperidin-4-Yl)-6-(2,2,2-Trifluoroethyl)Thieno[2,3-D]Pyrimidin-4-Amine(1628317-93-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1628317-93-0(Hazardous Substances Data)

1628317-93-0 Usage

Uses

Used in Pharmaceutical Industry:
N-(Piperidin-4-Yl)-6-(2,2,2-Trifluoroethyl)Thieno[2,3-D]Pyrimidin-4-Amine is used as a chemical intermediate for the development of new drugs. Its unique structure allows it to target specific biological pathways or receptors, which can be leveraged to create medications for various therapeutic areas.
Used in Chemical Research and Development:
In the field of chemical research and development, N-(Piperidin-4-Yl)-6-(2,2,2-Trifluoroethyl)Thieno[2,3-D]Pyrimidin-4-Amine serves as a valuable compound for exploring new chemical reactions and synthesis methods. Its properties can be studied to understand its reactivity, stability, and potential applications in creating novel chemical entities.

Check Digit Verification of cas no

The CAS Registry Mumber 1628317-93-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,2,8,3,1 and 7 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1628317-93:
(9*1)+(8*6)+(7*2)+(6*8)+(5*3)+(4*1)+(3*7)+(2*9)+(1*3)=180
180 % 10 = 0
So 1628317-93-0 is a valid CAS Registry Number.

1628317-93-0Downstream Products

1628317-93-0Relevant articles and documents

METHODS OF PROMOTING BETA CELL PROLIFERATION

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, (2018/06/30)

The present disclosure provides methods of promoting proliferation of a pancreatic cell. The methods are useful for the treatment of diabetes and other diseases characterized by impaired glucose tolerance.

Design and synthesis of benzylpiperidine inhibitors targeting the menin–MLL1 interface

Ren, Jing,Xu, Wei,Tang, Le,Su, Minbo,Chen, Danqi,Chen, Yue-Lei,Zang, Yi,Li, Jia,Shen, Jingkang,Zhou, Yubo,Xiong, Bing

, p. 4472 - 4476 (2016/08/25)

Menin is an essential oncogenic cofactor for mixed lineage leukemia (MLL)-mediated leukemogenesis, functioning through its direct interaction with MLL1 protein. Therefore, targeting the menin–MLL1 protein–protein interface represents a promising strategy

THIENOPYRIMIDINE AND THIENOPYRIDINE COMPOUNDS AND METHODS OF USE THEREOF

-

, (2016/04/20)

The present disclosure provides compounds and methods for inhibiting the interaction of menin with its upstream or downstream signaling molecules including but not limited to MLL1, MLL2 and MLL-fusion oncoproteins. Compounds of the disclosure may be used

COMPOSITIONS COMPRISING THIENOPYRIMIDINE AND THIENOPYRIDINE COMPOUNDS AND METHODS OF USE THEREOF

-

, (2014/09/29)

The present invention relates generally to thienopyrimidine and thienopyridine class compounds and methods of use thereof. In particular embodiments, the present invention provides compositions comprising thienopyrimidine class compounds and methods of us

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