Synthesis, molecular docking, and in silico ADME/Tox profiling studies of new 1-aryl-5-(3-azidopropyl)indol-4-ones: Potential inhibitors of SARS CoV-2 main protease
The virus SARS CoV-2, which causes the respiratory infection COVID-19, continues its spread across the world and to date has caused more than a million deaths. Although COVID-19 vaccine development appears to be progressing rapidly, scientists continue th
Domínguez-Villa, Francisco Xavier,Durán-Iturbide, Noemi Angeles,ávila-Zárraga, José Gustavo
supporting information
(2020/12/07)
Tetrahydropyrrolo[3,2-c]azepin-4-ones as a new class of cytotoxic compounds
Pyrroloazepinones 8a-j and 9a-j were designed by structural modification of lead compound 3. These compounds were tested on five tumor cell lines to determine the role of the azeto ring and the 2-methyl substituent in the cytotoxicity of compound 3. Our r
Martínez, Roberto,ávila, J. Gustavo,Ramírez, Ma. Teresa,Pérez, Araceli,Martínez, ángeles
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(2007/10/03)
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