163136-63-8Relevant articles and documents
4H-1,2,4-pyridothiadiazine 1,1-dioxides and 2,3-dihydro-4H-1,2,4- pyridothiadiazine 1,1-dioxides chemically related to diazoxide and cyclothiazide as powerful positive allosteric modulators of (R/S)-2-amino-3- (3-hydroxy-5-methylisoxazol-4-yl)propionic ac
Pirotte, Bernard,Podona, Tchao,Diouf, Ousmane,De Tullio, Pascal,Lebrun, Philippe,Dupont, Léon,Somers, Fabian,Delarge, Jacques,Morain, Philippe,Lestage, Pierre,Lepagnol, Jean,Spedding, Michael
, p. 2946 - 2959 (2007/10/03)
A series of 4H-1,2,4-pyridothiadiazine 1,1-dioxides and 2,3-dihydro-4H- 1,2,4-pyridothiadiazine 1,1-dioxides bearing various alkyl and aryl substituents on the 2-, 3-, and 4-positions was synthesized and tested as possible positive allosteric modulators o
Pyridothiadiazines
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, (2008/06/13)
The invention relates to a compound selected from those of formula (I): STR1 in which A, R 1, R 2 and R 4 are as defined in the description,and medicinal products containing the same which is useful for treating a pathology related to dysfunctioning of gl