Structure-based design and characterization of novel platforms for ricin and shiga toxin inhibition
Ribosome inhibiting proteins, RIPs, are a widespread family of toxic enzymes. Ricin is a plant toxin used as a poison and biological warfare agent; shiga toxin is a homologue expressed by pathogenic strains of E. coli. There is interest in creating effect
The invention relates to a compound selected from those of formula (I): STR1 in which A, R 1, R 2 and R 4 are as defined in the description,and medicinal products containing the same which is useful for treating a pathology related to dysfunctioning of gl
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(2008/06/13)
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