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3-Ethoxy-17-hydroxypregna-3,5-dien-20-one 17-acetate is a chemical compound derived from the pregnane class of steroid hormones. It is characterized by its unique molecular structure, featuring a 3-ethoxy group and a 17-acetate group, along with a 3,5-dien system. 3-Ethoxy-17-hydroxypregna-3,5-dien-20-one 17-acetate is known for its yellow crystalline appearance and is primarily used as an intermediate in the synthesis of other steroidal compounds, such as Progesterone.

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  • (17-acetyl-3-ethoxy-10,13-dimethyl-1,2,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl) acetate

    Cas No: 16319-93-0

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  • 16319-93-0 Structure
  • Basic information

    1. Product Name: 3-ethoxy-17-hydroxypregna-3,5-dien-20-one 17-acetate
    2. Synonyms: 3-ethoxy-17-hydroxypregna-3,5-dien-20-one 17-acetate;17-Acetyloxy-3-ethoxypregna-3,5-dien-20-one;3-Ethoxypregna-3,5-dien-17-ol-20-one-17-acetate;17α-Acetoxy-3-ethoxypregna-3,5-dien-20-one
    3. CAS NO:16319-93-0
    4. Molecular Formula: C25H36O4
    5. Molecular Weight: 400.55094
    6. EINECS: 240-396-4
    7. Product Categories: Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
    8. Mol File: 16319-93-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 515.9°Cat760mmHg
    3. Flash Point: 220.8°C
    4. Appearance: /
    5. Density: 1.11g/cm3
    6. Vapor Pressure: 0mmHg at 25°C
    7. Refractive Index: 1.541
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 3-ethoxy-17-hydroxypregna-3,5-dien-20-one 17-acetate(CAS DataBase Reference)
    11. NIST Chemistry Reference: 3-ethoxy-17-hydroxypregna-3,5-dien-20-one 17-acetate(16319-93-0)
    12. EPA Substance Registry System: 3-ethoxy-17-hydroxypregna-3,5-dien-20-one 17-acetate(16319-93-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 16319-93-0(Hazardous Substances Data)

16319-93-0 Usage

Uses

Used in Pharmaceutical Industry:
3-Ethoxy-17-hydroxypregna-3,5-dien-20-one 17-acetate is used as an intermediate in the preparation of Progesterone (P755900) impurity for the pharmaceutical industry. Its role in the synthesis process is crucial, as it helps in the development of medications that target various health conditions related to hormonal imbalances and reproductive health.
Chemical Properties:
The compound is characterized by its yellow crystalline appearance, which is a common feature among steroidal compounds. This property is indicative of its stability and purity, making it suitable for use in the pharmaceutical industry as a starting material for further chemical reactions and synthesis.

Check Digit Verification of cas no

The CAS Registry Mumber 16319-93-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,3,1 and 9 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 16319-93:
(7*1)+(6*6)+(5*3)+(4*1)+(3*9)+(2*9)+(1*3)=110
110 % 10 = 0
So 16319-93-0 is a valid CAS Registry Number.
InChI:InChI=1/C25H36O4/c1-6-28-19-9-12-23(4)18(15-19)7-8-20-21(23)10-13-24(5)22(20)11-14-25(24,16(2)26)29-17(3)27/h7,15,20-22H,6,8-14H2,1-5H3/t20-,21+,22+,23+,24+,25+/m1/s1

16319-93-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-Ethoxy-17-hydroxypregna-3,5-dien-20-one 17-acetate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:16319-93-0 SDS

16319-93-0Relevant articles and documents

METHOD FOR PREPARING MEDROGESTONE

-

Page/Page column 9, (2008/06/13)

A method for the preparation of medrogestone by heterogeneously palladium- catalysed isomerisation from 17-methyl-6-methylenepregn-4-ene-3,20-dione is described.

Sulfuric acid adsorbed on silica gel. A multipurpose acid catalyst

Chavez,Suarez,Diaz

, p. 2325 - 2339 (2007/10/02)

A series of acid catalyzed reactions like the dehydration of alcohols, conversion of ketones to 1,3-dioxolanes and their hydrolysis, α, β- unsaturated ketones to enol ethers, and alcohols to methyl-methoxyethyl ethers are performed efficiently in high yield with sulfuric acid adsorbed on silica gel as catalyst.

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