Synthesis of 4-Hydroxy-15-oxaandrost-4-en-3-one and other Potential Aromatase Inhibitors from Sandaracopimaric Acid
The stereoselective synthesis of 4-substituted androstenes (8β,14α) 30 and 36 related to inhibitors of the enzyme aromatase and 5α-reductase has been achieved in a short-step sequence from sandaracopimaric acid.The synthetic strategy is the stereoselectiv
Martin, M. Bordell,Mateos, A. Fernandez,Gonzalez, R. Rubio
p. 569 - 576
(2007/10/02)
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