- Synthesis of o-(2-Indolyl)benzoic Acids from Indole
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Treatment of 6H-isoindoloindol-6-ones with potassium t-butoxide/t-butyl alcohol containing a small amount of water at 82 deg C afforded o-(2-indolyl)benzoic acids in good yields.
- Itahara, Toshio
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Read Online
- Chemical compounds containing bis(triazolo)triazine structures and methods thereof
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Chemical compounds having a bis(triazolo)triazine structure, including complexes and salts thereof, may be useful in either an intermediate or final product.
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Page column 6-7
(2010/02/09)
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- Simulated sunlight-induced photodegradations of triasulfuron and cinosulfuron in aqueous solutions
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To elucidate the photochemical behavior of two sulfonylureas (cinosulfuron and triasulfuron) for which the chemical formulas are relatively close, their photodegradation was studied in water. All experiments were carried out under laboratory conditions using a xenon arc lamp as the source of radiation to simulate environmental conditions. Polychromatic quantum efficiencies were calculated to determine the photochemical pesticide lifetimes at pH 7, and a comparison with hydrolysis lifetimes has been performed. The results obtained showed clearly that at pH 7, photodegradation becomes a more important pathway than chemical degradation. HPLC-DAD was used to study the kinetics for both sulfonylureas and their photoproducts, whereas HPLC-MS (ESI in positive and negative modes) was used to identify photoproducts. These results suggest that the photodegradation of these two sulfonylureas proceeds via a number of reaction pathways: (1) cleavage of the sulfonylurea bridge; (2) desulfonylation, which can proceed either by a carbon-sulfur cleavage or a nitrogen-sulfur cleavage; (3) O-demethylation of methoxy moieties present on the triazine ring; and (4) O-dealkylation of benzene derivatives. In addition, it was found that the desulfonylation represented the main step and that it was wavelength dependent.
- Vulliet,Emmelin,Grenier-Loustallot,Paisse,Chovelon
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p. 1081 - 1088
(2007/10/03)
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- Process for making 2-amino-4, 6-dialkoxy-1, 3, 5-triazines
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A method is provided for making ammelide ethers, such as a 2-amino-4,6-dialkoxy-1,3,5-triazine. A 2-amino-4,6-dihalo-1,3,5-triazine (ADXT) is synthesized in the presence of an aromatic organic solvent, and reaction is effected directly between the (ADXT) synthesis mixture and an alkali metal C(1-4) alkoxide and C(1-4) alkanol, including contact through a static mixer. These ammelide ethers are useful as intermediates for making N-phenylsulfonyl-N-triazinylureas, which have herbicidal and growth regulating properties.
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- Process for producing sulfonylureas
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There is described a novel process for producing sulfonylureas of formula I STR1 wherein R1 is hydrogen or alkyl, R2 is STR2 E is =N-- or =CH--, R3 is alkyl, alkoxy or halogen, R4 is alkyl, cycloalkyl, alkoxy, halogen, alkoxy-alkyl, halo-alkyl or halo-alkoxy, R5 is hydrogen or alkyl, T is a substituted phenyl group STR3 Y is hydrogen or halogen, X is hydrogen, halogen, alkyl, halo-alkyl, alkenyl, halo-alkenyl, alkynyl, alkoxy, halo-alkoxy, alkylthio, alkylsulfinyl, alkylsulfonyl, halo-alkylthio, alkylsulfonyloxy, phenylsulfonyloxy, phenylsulfonyloxy mono- or polysubstituted by alkyl, or is di-alkylsulfamoyl, and A is a bridge member which has 3 or 4 atoms and which contains 1 or 2 hetero atoms, selected from the group consisting of oxygen, sulfur and nitrogen, the said process comprising reacting a silfonamide of the formula II in the presence of a base, with diphenyl carbonate to form a salt of a phenyl carbamate converting this salt into the free phenyl carbamate and reacting this further with an amine. Sulfonylureas are herbicidally effective compounds.
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- 1,3-Dipolar Character of Six-membered Aromatic Rings. Part 48. Novel Conversions of Pyridines to Isoquinolines
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1-Heteroaryl-3-oxidopyridinium dimers with dienamines give cycloadducts which are dehydrogenated to 'mixed dimer' of the corresponding 2-heteroaryl-4-oxidoisoquinolinium with the starting 1-heteroaryl-3-oxidopyridinium.The 'mixed dimer' (21) is also effectively prepared by a two-step sequence of a novel intramolecular oxidation-reduction, followed by oxidation of the resulting alcohol.The 'mixed dimers' undergo reversible thermal dissociation and in one case the corresponding monomers could be trapped as various cycloadducts.
- Katritzky, Alan R.,Dennis, Nicholas,Dowlatshahi, Hossein A.
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p. 331 - 342
(2007/10/02)
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