163704-72-1

Basic information

• Product Name: 2,6-DIISOPROPYL-4-NITROANILINE
• Synonyms: 2,6-DIISOPROPYL-4-NITROANILINE
• CAS NO: 163704-72-1
• Molecular Formula: C₁₂H₁₈N₂O₂
• Molecular Weight: 222.28
• Product Categories: pharmacetical
• Mol File: 163704-72-1.mol

Chemical Properties

• Melting Point: 125-126 °C(Solv: ethyl ether (60-29-7); hexane (110-54-3))
• Boiling Point: 333 °C at 760 mmHg
• Flash Point: 155.2 °C
• Appearance: /
• Density: 1.091 g/cm³
• Vapor Pressure: 0.000141mmHg at 25°C
• Refractive Index: 1.555
• PKA: 0.70±0.20(Predicted)
• CAS DataBase Reference: 2,6-DIISOPROPYL-4-NITROANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-DIISOPROPYL-4-NITROANILINE(163704-72-1)
• EPA Substance Registry System: 2,6-DIISOPROPYL-4-NITROANILINE(163704-72-1)

Safety Data

• Hazardous Substances Data: 163704-72-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2,6-DIISOPROPYL-4-NITROANILINE is used as a synthetic intermediate for the production of various pharmaceuticals. It plays a crucial role in the synthesis of active pharmaceutical ingredients, contributing to the development of new drugs and therapies.
Used in Agrochemical Industry:
In the agrochemical industry, 2,6-DIISOPROPYL-4-NITROANILINE serves as an intermediate in the synthesis of various agrochemicals. It helps in the development of pesticides, herbicides, and other agricultural chemicals that are essential for crop protection and increased agricultural productivity.
Used in Dye and Pigment Industry:
2,6-DIISOPROPYL-4-NITROANILINE is used as a synthetic intermediate in the production of dyes and pigments. It contributes to the creation of a wide range of colorants used in various applications, including textiles, plastics, inks, and coatings.
Used in Organic Compounds Synthesis:
2,6-DIISOPROPYL-4-NITROANILINE is also utilized as an intermediate in the synthesis of other organic compounds. Its unique chemical structure allows it to be a valuable building block in the preparation of various organic molecules for different industrial applications.

InChI:InChI=1/C12H18N2O2/c1-7(2)10-5-9(14(15)16)6-11(8(3)4)12(10)13/h5-8H,13H2,1-4H3

Upstream product

• 24544-04-5 2,6-diisopropylbenzenamine 
• 163704-71-0 N-(2,6-diisopropylphenyl)tosylamide 
• 474328-43-3 N-(2,6-diisopropyl-4-nitrophenyl)-4-methylbenzenesulfonamide 

Downstream Products

• 455288-51-4 4-amino-2,6-diisopropylaniline 
• 91563-77-8 3,5-diisopropylnitrobenzene 
• 928790-08-3 [1-(3,5-diisopropyl-phenylcarbamoyl)-2-methyl-propyl]-methyl-carbamic acid tert-butyl ester 
• 7544-57-2 3,5-diisopropylaniline 
• 259225-37-1 2,6-diisopropyl-4-tritylaminoaniline 
• 259225-25-7 N-[1-butyl-4-(3-methoxyphenyl)-1,2-dihydro-2-oxo-1,8-naphthyridin-3-yl]-N'-(2,6-diisopropyl-4-tritylaminophenyl)urea 
• 873194-89-9 1-{1-butyl-4-[3-(3-chloro-propoxy)-phenyl]-2-oxo-1,2-dihydro-[1,8]naphthyridin-3-yl}-3-[2,6-diisopropyl-4-(trityl-amino)-phenyl]-urea 
• 873194-81-1 acetic acid 2-[3-(1-butyl-3-{3-[2,6-diisopropyl-4-(trityl-amino)-phenyl]-ureido}-2-oxo-1,2-dihydro-[1,8]naphthyridin-4-yl)-phenoxy]-ethyl ester 
• 873194-82-2 acetic acid 3-[3-(1-butyl-3-{3-[2,6-diisopropyl-4-(trityl-amino)-phenyl]-ureido}-2-oxo-1,2-dihydro-[1,8]naphthyridin-4-yl)-phenoxy]-propyl ester 
• 873194-83-3 acetic acid 4-[3-(1-butyl-3-{3-[2,6-diisopropyl-4-(trityl-amino)-phenyl]-ureido}-2-oxo-1,2-dihydro-[1,8]naphthyridin-4-yl)-phenoxy]-butyl ester 
• 873194-93-5 1-{1-butyl-4-[3-(3-diethylamino-propoxy)-phenyl]-2-oxo-1,2-dihydro-[1,8]naphthyridin-3-yl}-3-[2,6-diisopropyl-4-(trityl-amino)-phenyl]-urea 
• 873194-94-6 1-{1-butyl-2-oxo-4-[3-(3-pyrrolidin-1-yl-propoxy)-phenyl]-1,2-dihydro-[1,8]naphthyridin-3-yl}-3-[2,6-diisopropyl-4-(trityl-amino)-phenyl]-urea 

Relevant articles and documents

Synthesis method of diafenthiuron impurity C

The invention provides a preparation method of a diafenthiuron impurity C. According to the preparation method of the diafenthiuron impurity C, 2, 6-isopropylaniline, 4-toluenesulfonyl chloride, phenol, N, N-diisopropylethylamine and the like are used as

Facile synthesis of 2,3,5,6-tetrabromo-4-methyl-nitrocyclohexa-2,5-dien-1- one, a mild nitration reagent

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Synthesis and biological activity of novel 4-phenyl-1,8-naphthyridin-2(1H)- on-3-yl ureas: Potent acyl-CoA:cholesterol acyltransferase inhibitor with improved aqueous solubility

4-Aryl-1,8-naphthyridin-2(1H)-on-3-yl urea derivatives with hydrophilic groups were synthesized in order to improve aqueous solubility and pharmacokinetic property. SMP-797 possessing (4-aminophenyl)ureido and 3-(hydroxypropoxyphenyl) moieties showed pote

Synthesis of SMP-797: A new potent ACAT inhibitor

A potent ACAT (acyl-CoA: cholesterol acyltransferase) inhibitor SMP-797 was effectively synthesized by the urea formation of 3-amino-4-aryl-1,8- naphthyridin-2(1H)-one and 4-amino-2,6-diisopropylamine. The synthesis of the former compound involved the Suzuki coupling reaction as a key step, and the latter was prepared by the 4-selective nitration of 2,6-diisopropylaniline using 2,3,5,6-tetrabromo-4-methyl-4-nitro-2,5-cyclohexadienone.

Substituent effects on edge-to-face aromatic interactions

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