cas 163768-50-1, Auristatin F | Articles data ｜lookchem

Welcome to LookChem.com Sign In|Join Free

Article Database

Home > CAS Article list >
163768-50-1

Articles about 163768-50-1Total 2 be found

Article title
Article abstract
Author
Journal number and time
Download

PROSTATE-SPECIFIC MEMBRANE ANTIGEN ANTIBODY DRUG CONJUGATES
This invention relates to prostate-specific membrane antigen (PSMA) antibodies and antibody drug conjugates comprising at least one non-naturally-encoded amino acid. Disclosed herein are αPSMA antibodies with one or more non-naturally encoded amino acids and further disclosed are antibody drug conjugates wherein the αPSMA antibodies of the invention are conjugated to one or more toxins. Also disclosed herein are non-natural amino acid dolastatin analogs that are further modified post-translationally, methods for effecting such modifications, and methods for purifying such dolastatin analogs. Typically, the modified dolastatin analogs include at least one oxime, carbonyl, dicarbonyl, and/or hydroxylamine group. Further disclosed are methods for using such non-natural amino acid antibody drug conjugates, dolastatin analogs, and modified non-natural amino acid dolastatin analogs, including therapeutic, diagnostic, and other biotechnology uses.
-
(2014/01/08)

COMPOSITIONS CONTAINING, METHODS INVOLVING, AND USES OF NON-NATURAL AMINO ACID LINKED DOLASTATIN DERIVATIVES
Disclosed herein are non-natural amino acids and dolastatin analogs that include at least one non-natural amino acid, and methods for making such non-natural amino acids and polypeptides. The dolastatin analogs can include a wide range of possible functionalities, but typically have at least one oxime, carbonyl, dicarbonyl, and/or hydroxylamine group. Also disclosed herein are non-natural amino acid dolastatin analogs that are further modified post-translationally, methods for effecting such modifications, and methods for purifying such dolastatin analogs. Typically, the modified dolastatin analogs include at least one oxime, carbonyl, dicarbonyl, and/or hydroxylamine group. Further disclosed are methods for using such non-natural amino acid dolastatin analogs and modified non-natural amino acid dolastatin analogs, including therapeutic, diagnostic, and other biotechnology use.
-
(2013/02/28)

More Articles about upstream products of 163768-50-1

More Articles about downstream products of 163768-50-1

Chemical Properties

Boiling Point: 894.4±65.0 °C(Predicted)
Density: 1.112±0.06 g/cm3(Predicted)
Solubility:DMSO (Slightly), Methanol (Slightly, Heated)
Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere
PKA: 3.56±0.10(Predicted)

Show more

Global suppliers and manufacturers of 163768-50-1total 20 suppliers on LookChem

Company Name
Business Type
Min Order
FOB Price
Main Products
Contact

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd
Business Type:Trading Company
Min Order:1 Gram
FOB Price:No Data
Main Products:86
Country:

SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Business Type:Lab/Research institutions
Min Order:4 Kilogram
FOB Price:No Data
Main Products:35
Country:

Zibo Dorne chemical technology co. LTD
Business Type:Lab/Research institutions
Min Order:1 Kilogram
FOB Price:No Data
Main Products:69
Country:

Xiamen Jenny Chemical Technology Co., Ltd.
Business Type:Trading Company
Min Order:1 Milligram
FOB Price:No Data
Main Products:33
Country:

Guangdong Juda Chemical Industrial Co.,Limited
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:30
Country:

Henan Kanbei Chemical Co.,LTD
Business Type:Lab/Research institutions
Min Order:No Data
FOB Price:No Data
Main Products:61
Country:

Asure Biochem CO.,LTD.
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:11
Country:

BOC Sciences
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:41
Country:

Chemsigma International Co.,Ltd.
Business Type:Lab/Research institutions
Min Order:No Data
FOB Price:No Data
Main Products:84
Country:

ZHEJIANG JIUZHOU CHEM CO.,LTD
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:27
Country:

Wuhan Sun-shine Bio-technology Corporation Limited
Business Type:Lab/Research institutions
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

Changzhou Extraordinary Pharmatech co.,LTD
Business Type:Lab/Research institutions
Min Order:1 Gram
FOB Price:No Data
Main Products:1
Country:

Toda Biotechnology Co., Limited.
Business Type:Trading Company
Min Order:1 Kilogram
FOB Price:USD $ 90.0-100.0 / Kilogram
Main Products:1
Country:

ShenZhen InnoSyn Biotech Co.,Ltd
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

Zhejiang Huida Biotech Co., Ltd
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

Wuhan MoonZY Biological Technology Co.,Ltd
Business Type:Lab/Research institutions
Min Order:1 Gram
FOB Price:No Data
Main Products:1
Country:

SHANGHAI ZZBIO CO., LTD.
Business Type:Lab/Research institutions
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

SUZHOU AUSUN CHEMICAL CO., LTD。
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

Shanghai Haoyuan Chemexpress Co., Ltd.
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

NovaChemistry
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 163768-50-1

About us - Payment - Contact us - Links - Help Center - Disclaimer
SiteMap | Manufacturers | VIP Product | Suppliers | CAS | New CAS | Cas Database | Article Data | Chemical Catalog | Product Name

©2008 LookChem.com,License:ICP NO.:Zhejiang16009103 complaints:service@lookchem.com
[Hangzhou]86-571-87562588,87562561,87562573 Our Legal adviser: Lawyer