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2-AMINO-4,6-DI-TERT-BUTYLPHENOL, with the molecular formula C14H23NO, is a white crystalline solid at room temperature. It is a chemical compound that is insoluble in water and is widely recognized for its antioxidant properties. 2-AMINO-4,6-DI-TERT-BUTYLPHENOL is capable of inhibiting the oxidation of other substances, which makes it a crucial additive in various industrial applications where product stability and shelf life are of paramount importance.

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  • 1643-39-6 Structure
  • Basic information

    1. Product Name: 2-AMINO-4,6-DI-TERT-BUTYLPHENOL
    2. Synonyms: 2-AMINO-4,6-DI-TERT-BUTYLPHENOL;4,6-Di-tert-butyl-2-aminophenol;2-AMino-4,6-di-tert.-butyl-phenoxyl
    3. CAS NO:1643-39-6
    4. Molecular Formula: C14H23NO
    5. Molecular Weight: 221.34
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1643-39-6.mol
  • Chemical Properties

    1. Melting Point: 171-172 °C
    2. Boiling Point: 297.9±40.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 0.990±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
    8. Solubility: N/A
    9. PKA: 11.36±0.23(Predicted)
    10. CAS DataBase Reference: 2-AMINO-4,6-DI-TERT-BUTYLPHENOL(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-AMINO-4,6-DI-TERT-BUTYLPHENOL(1643-39-6)
    12. EPA Substance Registry System: 2-AMINO-4,6-DI-TERT-BUTYLPHENOL(1643-39-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1643-39-6(Hazardous Substances Data)

1643-39-6 Usage

Uses

Used in Polymer and Plastics Industry:
2-AMINO-4,6-DI-TERT-BUTYLPHENOL is used as an antioxidant for the production of polymers and plastics. Its role in this industry is to prevent the degradation of these materials, thereby extending their useful life and maintaining their structural integrity.
Used in Fuel and Lubricant Industry:
In the fuel and lubricant industry, 2-AMINO-4,6-DI-TERT-BUTYLPHENOL is utilized as a stabilizer. It helps to prevent the degradation of fuels and lubricants that can occur due to exposure to oxygen and other reactive substances, ensuring their performance and longevity.

Check Digit Verification of cas no

The CAS Registry Mumber 1643-39-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,4 and 3 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1643-39:
(6*1)+(5*6)+(4*4)+(3*3)+(2*3)+(1*9)=76
76 % 10 = 6
So 1643-39-6 is a valid CAS Registry Number.

1643-39-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-amino-4,6-ditert-butylphenol

1.2 Other means of identification

Product number -
Other names 2,4-di-tert-butyl-6-aminophenol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1643-39-6 SDS

1643-39-6Relevant articles and documents

Molecular structures, DFT studies and their photophysical properties in solution and solid state. Microwave-assisted multicomponent synthesis of organotin bearing Schiff bases

Cantón-Díaz, Arelly M.,Mu?oz-Flores, Blanca M.,Moggio, Ivana,Arias, Eduardo,Turlakov, Gleb,Del Angel-Mosqueda, Casiano,Ramirez-Montes, Pedro I.,Jiménez-Pérez, Víctor M.

, p. 642 - 650 (2019)

A couple of luminescent organotin compounds derivated from ligands-ONO were obtained by multicomponent microwave assisted synthesis in short time (15 min) and good yields: ((E)-8, 8-8-diphenylbenzo[d] naphtho [1,2-h][1,3,6,2] dioxazastannonine (1) and (E)

Reactions of isomeric 3,6- and 3,5-di-tert-butyl-ortho-benzoquinones

Vol'eva, V. B.,Prokof'eva, T. I.,Prokof'ev, A. I.,Belostotskaya, I. S.,Komissarova, N. L.,Ershov, V. V.

, p. 1720 - 1724 (1995)

The interaction of 3,6-di-tert-butyl-ortho-benzoquinone (1) and 3,5-di-tert-butyl-ortho-benzoquinone (2) with NH3 in water-alcohol medium and with (NH4)2 CO3 in a solid phase has been studied.Redox processes with participation of a nucleophile of the medi

Fluorescent Molecular Rotors of Organoboron Compounds from Schiff Bases: Synthesis, Viscosity, Reversible Thermochromism, Cytotoxicity, and Bioimaging Cells

Ibarra-Rodr??guez, Marisol,Mu?oz-Flores, Blanca M.,Dias, H. V. Rasika,Sánchez, Mario,Gomez-Trevi?o, Alberto,Santillan, Rosa,Farfán, Norberto,Jiménez-Pérez, Víctor M.

, p. 2375 - 2385 (2017)

We report the design, synthesis, and characterization of two new fluorescent molecular rotors of boron derived from Schiff bases: (2,4,8,10-tetra-tert-butyl-6-phenyldibenzo[d,h][1,3,6,2]dioxazaboronine (3) and 1,4-bis(2,4,8,10-tetra-tert-butyldibenzo[d,h][1,3,6,2]dioxazaboronin-6-yl)benzene (4), as well as the free ligand 2-[[(3,5-di-tert-butyl-2-hydroxyphenyl)imino]methyl]-4,6-di-tert-butylphenol 1. All compounds were fully characterized by NMR (1H,11B, and13C), IR, UV/vis, fluorescence spectroscopy, and high-resolution mass spectrometry. The crystal structures of 3 and 4 showed tetracoordinated boron atoms with semiplanar skeleton ligands. The free rotation of the fluorescent molecular rotor, only observed in the binuclear compound, was decreased with increasing viscosity, while the quantum yield was increased. Interestingly, the property of reversible thermochromism was found in organoboron 4 in the solid state. DFT calculations to determine the both complexes have free rotation around the CPh-B1 bond. The boron compounds 3 and 4 have shown low cytotoxicity activity in cell line A-431 and low green staining in cells.

Tridentate [ONO] tungsten coordination compound and optical application thereof

-

, (2021/05/29)

The invention provides a tridentate [ONO] tungsten coordination compound and optical application thereof, and the tridentate [ONO] tungsten coordination compound is divided into but not limited to three structures, namely a structure I, a structure II and

Metal-Free Oxidative Condensation of Catechols, Aldehydes and NH4OAc towards Benzoxazoles

Dong, Jianyu,Geng, Furong,Su, Lebin,Wu, Shaofeng,Yin, Shuang-Feng,Zhou, Dan,Zhou, Yongbo

supporting information, p. 3607 - 3614 (2021/07/28)

Benzoxazoles extensively exist in biologically active compounds, natural products, pharmaceuticals and functional materials. Thus, facile and green synthesis of such valuable compounds from easily available substrates will make a contribution to drug, material, and fine chemistry. A method for the synthesis of benzoxazoles from catechols, aldehydes and ammonium acetate is developed using NaIO4 as oxidant under metal- and additive-free conditions. A broad range of benzoxazoles including some fluorescent whitening agents, JTP-426467 and tafamidis analogues are synthesized in 56–95% yields with outstanding functional group tolerance. Mechanistic investigations suggest that an interesting o-iminocyclohexa-diene alcohol intermediate is involved in the reaction. These salient features of the protocol make it an alternative for the synthesis of benzoxazoles. (Figure presented.).

Controllable synthesis of 2- And 3-aryl-benzomorpholines from 2-aminophenols and 4-vinylphenols

Dong, Kui,Jin, Xiao-Ling,Chen, Shihao,Wu, Li-Zhu,Liu, Qiang

, p. 7941 - 7944 (2020/08/14)

We present herein a method for the controllable synthesis of 3-aryl-benzomorpholine and 2-aryl-benzomorpholine cycloadducts via cross-coupling/annulation between electron-rich 2-aminophenols and 4-vinylphenols. Molecular oxygen was successfully used in the reaction as the terminal oxidant and the complete inversion of chemoselectivity was achieved by the adjustment of the solvents and bases at room temperature.

A new bis-phenolate mesoionic carbene ligand for early transition metal chemistry

Baltrun, Marc,Watt, Fabian A.,Schoch, Roland,W?lper, Christoph,Neuba, Adam G.,Hohloch, Stephan

, p. 14611 - 14625 (2019/10/16)

We report the synthesis of a new pincer-type triazolylidene ligand precursor H3L[Cl] with redox-active 3,5-di-tert-butylphenolate substituents on a multigram scale following a converging ten-step route. The potential of this new mesoionic carbe

Synthesis of Mono- and Dinuclear Vanadium Complexes and Their Reactivity toward Dehydroperoxidation of Alkyl Hydroperoxides

Schmidt, Anna-Corina,Hermsen, Marko,Rominger, Frank,Dehn, Richard,Teles, Joaquim Henrique,Sch?fer, Ansgar,Trapp, Oliver,Schaub, Thomas

, p. 1319 - 1332 (2017/02/15)

Several vanadium(V) complexes with either dipic-based or Schiff base ligands were synthesized. The complexes were fully characterized by elemental analysis, IR, 1H, 13C, and 51V NMR spectroscopy, as well as mass spectrometry and X-ray diffraction. Furthermore, they were tested toward their catalytic deperoxidation behavior and a significant difference between 4-heptyl hydroperoxide and cyclohexyl hydroperoxide was observed. In the case of 4-heptyl hydroperoxide, the selectivity toward the corresponding ketone was higher than with cyclohexyl hydroperoxide. DFT calculations performed on the vanadium complex showed that selective decomposition of secondary hydroperoxides with vanadium(V) to yield the corresponding ketone and water is indeed energetically feasible. The computed catalytic path, involving cleavage of the O-O bond, hydrogen transfer, release of ketone/water, and finally addition of hydroperoxide, can proceed without the generation of radical species.

Improvement in Aluminum Complexes Bearing Schiff Bases in Ring-Opening Polymerization of ?-Caprolactone: A Five-Membered-Ring System

Lee, Chieh-Ling,Lin, Ya-Fan,Jiang, Man-Ting,Lu, Wei-Yi,Vandavasi, Jaya Kishore,Wang, Li-Fang,Lai, Yi-Chun,Chiang, Michael Y.,Chen, Hsuan-Ying

, p. 1936 - 1945 (2017/06/13)

A series of five- and six-membered-ring Al complexes bearing Schiff bases was synthesized and their application to the ring-opening polymerization of ?-caprolactone (CL) was studied. The five-membered-ring Al complexes have been shown to have a significan

Compositions for Treatment of Cystic Fibrosis and Other Chronic Diseases

-

, (2015/09/22)

The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one ABC Transporter modulator compound of Formula A, Formula B, Formula C, or Formula D. The invention also relates to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions.

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