- Buchwald-Hartwig reactions of monohaloflavones
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The article describes the amination of different monobromo- or monochloroflavones with primary and secondary alkylamines and aniline derivatives by Buchwald-Hartwig reaction. The influence of the phosphine ligands used is described. The use of amino acid derivatives as a nitrogen source is also demonstrated. This latter reaction allows the synthesis of unique flavone-amino-acid conjugates.
- Knya, Krisztina,Pajts, Dvid,Kiss-Szikszai, Attila,Patonay, Tams
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supporting information
p. 828 - 839
(2015/01/30)
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- Triazine-based mesoporous covalent imine polymers as solid supports for copper-mediated chan-lam cross-coupling N-arylation reactions
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The synthesis of a novel mesoporous covalent imine polymeric (MCIPs) material, involving simple Schiff-base chemistry, is reported. This highly functionalised nitrogen-rich material acts as a good support for immobilising CuII ions, exhibiting excellent catalytic activity in promoting the Chan-Lam cross-coupling reaction between biologically active amines and arylboronic acids. The performance of this catalyst is also evident from its broad substrate scope, high stability, real heterogeneity, mild reaction conditions and reusability without loss of activity. The observed results will provide additional scope on the design and catalytic applications of this emerging class of materials.
- Puthiaraj, Pillaiyar,Pitchumani, Kasi
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p. 8761 - 8770
(2014/07/21)
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