164518-66-5Relevant articles and documents
Method for the treatment of overactive bladder
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, (2008/06/13)
Treatment or prevention of overactive bladder or urinary incontinence in mammals, particularly humans, using (S)-N-[2-(3,4-dichlorophenyl)-4-[4-(2-oxoperhydropyrimidin-1-yl)piperidino]butyl]-N-methylbenzamide, pharmaceutically-advantageous salts of the compound, methods of use of the compound, either alone or in combination with other pharmacological agents, and pharmaceutical compositions useful in practising the methods of the invention.
Therapeutic heterocycles which antagonize neurokinin receptors
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, (2008/06/13)
Compounds of formula I STR1 wherein G, J, L, M, m and D have any of the meanings given in the specification, their N-oxides, and their pharmaceutically acceptable salts are nonpeptide antagonists of neurokinin A and useful for the treatment of asthma, etc. Also disclosed are pharmaceutical compositions, processes for preparing the compounds of formula I and intermediates.