Synthesis and pharmacological evaluation of phenylacetamides as sodium- channel blockers
The synthesis and structure-activity relationships of a series of phenylacetamides related to N-[3-(2,6-dimethyl-1-piperidinyl)propyl]-α- phenylbenzeneacetamide (1) (PD85639) acting at the voltage-dependent Na+ channel are described. All struct
Roufos,Hays,Dooley,Schwarz,Campbell,Probert Jr.
p. 268 - 274
(2007/10/02)
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