164915-57-5

Basic information

• Product Name: 7-Nitro-3(2H)-benzofuranone
• Synonyms: 7-Nitro-3(2H)-benzofuranone;7-Methoxy-3-Benzofuranone;7-Nitrobenzofuran-3(2H)-one
• CAS NO: 164915-57-5
• Molecular Formula: C8H5NO4
• Molecular Weight: 179.1296
• Mol File: 164915-57-5.mol

Chemical Properties

• Boiling Point: 300.8°C at 760 mmHg
• Flash Point: 126.6°C
• Appearance: /
• Density: 1.262g/cm³
• Vapor Pressure: 0.00109mmHg at 25°C
• Refractive Index: 1.562
• CAS DataBase Reference: 7-Nitro-3(2H)-benzofuranone(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Nitro-3(2H)-benzofuranone(164915-57-5)
• EPA Substance Registry System: 7-Nitro-3(2H)-benzofuranone(164915-57-5)

Safety Data

• Hazardous Substances Data: 164915-57-5(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
7-Nitro-3(2H)-benzofuranone is utilized as a reagent in organic synthesis for the preparation of various chemical compounds. Its nitro-substituted benzofuranone structure allows for versatile reactions and transformations, making it a valuable component in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 7-Nitro-3(2H)-benzofuranone is employed as a key intermediate in the synthesis of various drugs. Its unique chemical properties enable the development of new pharmaceutical agents with potential therapeutic benefits.
Used in Agrochemical Industry:
7-Nitro-3(2H)-benzofuranone is also used in the agrochemical industry for the production of pesticides and other agrochemicals. Its chemical properties contribute to the development of effective and targeted pest control solutions.
Used in Dye Industry:
In the dye industry, 7-Nitro-3(2H)-benzofuranone is employed for the synthesis of various dyes and pigments. Its yellow crystalline solid form and strong smell make it a suitable candidate for the development of colorants used in various applications.
Used in Antimicrobial Applications:
7-Nitro-3(2H)-benzofuranone has been studied for its potential antimicrobial properties. It has shown to exhibit inhibitory effects against various microorganisms, making it a promising candidate for the development of antimicrobial agents.
Used in Antifungal Applications:
7-Nitro-3(2H)-benzofuranone has also demonstrated antifungal properties, making it a potential candidate for the development of antifungal agents to combat fungal infections.
Used in Antiproliferative Applications:
7-Nitro-3(2H)-benzofuranone has shown antiproliferative properties, indicating its potential use in the development of agents that can inhibit the proliferation of cells, particularly in the context of cancer treatment.
It is crucial to handle 7-Nitro-3(2H)-benzofuranone with care, as it can be hazardous if not properly managed. Proper safety measures should be taken during its synthesis, storage, and use to minimize potential risks.

InChI:InChI=1/C9H8O3/c1-11-8-4-2-3-6-7(10)5-12-9(6)8/h2-4H,5H2,1H3

Upstream product

• 179071-51-3 ethyl 2,3-dihydro-7-nitrobenzofuran-3-on-2-ylcarboxylate 

Relevant articles and documents

3-(benzofuran-7-yl)-6-haloalkyluracils

Herbicidal 3-(benzofuran-7-yl)-6-haloalkyluracils of the formula STR1 in which M is fluoroalkyl (C1-6); D is hydrogen, alkyl (C1-6), or alkoxy(C1-6)-carbonyl; E is hydrogen or alkyl (C1-6), or D and E taken together are --CH2 CH2 --; R is hydrogen, amino, alkyl (C1-6), 2-alkenyl (C3-6), 2-alkynyl (C3-6), alkoxy(C1-6)methyl, benzyl, amino, fluoroalkyl (C1-6), alkoxy (C1-6)-carbonylmethyl; or cyanoalkyl (C1-6) having preferably one cyano group; X is hydrogen, fluorine, chlorine, bromine, cyano, alkyl(C1-6), haloalkyl(C1-6), haloalkoxy(C1-6), or alkoxy(C1-6); Y is hydrogen, alkyl (C1-6), fluorine, chlorine, or bromine; and Z is CH2, C=O, C=S, --CH(OH)--, --CH2 CH2 --, --CH=CH--, --(C=O)CH2 --; or C=N--O--R' wherein R' is alkyl(C1-6).