- Novel water-soluble red-emitting poly(p -phenylenevinylene) derivative: Synthesis, characterization, and fluorescent acetylcholinesterase assays
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A new cyano-substituted poly(p-phenylenevinylene) (PPV) derivative, MEOPS-CNPPV, is synthesized through Knoevenagel condensation of anionic diacetonitrile and neutral dialdehyde and characterized by 1H NMR, IR, elemental analysis, and gel-permeation chromatography (GPC). To our knowledge, the polymer is the first water-soluble red-emitting PPV derivative. The absorption and emission wavelength of this water-soluble conjugated polymer (CP) depend on the solvent. In buffer solution, the fluorescence of MEOPS-CNPPV is quenched by cationic dinitrobenzene derivatives. Further research indicates that dinitrobenzene derivative with a more flexible structure exhibits a larger Ksv. Making use of the charge reversal of dinitrobenzene-modified substrate, a "turn-on" method is developed for AChE activity assay with the new polymer as a fluorophore. This convenient and direct fluorometric assay thus provides a platform for novel red-emitting sensory systems.
- Zhang, Wenjun,Zhu, Linna,Qin, Jingui,Yang, Chuluo
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experimental part
p. 12059 - 12064
(2011/12/05)
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- Novel synthesis and characterization of some new-2-(R) phenyl- 4-(-4-bromo-2-fluoro benzylidene)-oxazol-5-ones
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In the present study a series of some new 2-(substituted) phenyl- 4-(4-bromo-2-fluoro benz-ylidene)-oxazol-5-ones (2a-2j) were synthesized by the condensation of selected substituted benzoyl glycine (1a-1j) with 4-bromo-2-fluoro benzaldehyde in the presence of fused sodium acetate and acetic anhydride. The constitution of the newly synthesized compounds has been supported by their physical properties, elemental analysis, colour, m.p, IR spectral analysis data.
- Pareek, Alok K.,Joseph,Seth, Daya S.
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experimental part
p. 1533 - 1536
(2011/10/12)
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- Synthesis, characterization and biological activity of Cu(II) chelates with some amino acid derivatives
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The complexing behaviour of seventeen amino acid derivatives towards Cu(II) has been studied.Complexes of the types Cu(RH)*xH2O, Cu(RH).Cu(OH)2*xH2O and Cu(R'H)2*yH2O have been prepared and characterized by IR, ESR, electronic spectral, magnetic moment and analytical data.On the basis of differences and direction of the shifts in the IR frequencies of vas OCO and vs OCO modes and ESR spectra, bonding modes of carboxylate group have been established.Biological activitu of complexes is more than that of the free metal ion and the ligands.
- Nandi, M. M.,Choudhury, J.,Tarat, S.
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p. 288 - 291
(2007/10/02)
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