Chiral 1,4-diazepinones and 1,4-thiazepinones by diastereoselective ring chain transformation of α,β-unsaturated lactones or lactams
Butenolides or α,β-unsaturated lactams 1 react with 1,2-diamines, cysteamine or 2-aminothiophenol by addition and ring transformation giving new chiral, hydrogenated or partly hydrogenated 7-(α-hydroxyalkyl) and 7-(α-aminoalkyl)-1,4-diazepin-5-ones and 1,