165898-60-2Relevant articles and documents
Chemical and pharmacological properties of new tetrahydropyrimido-[2,1-f]-purines
Pawlowski,Drabczynska,Gorczyca,Malec,Modzelewski
, p. 453 - 455 (2007/10/02)
Following a research program on piperazinoalkyl-substituted tricyclic purines, a number of N-9-aryl(alkyl)-piperazinopropyl substituted tetrahydropyrimido-[2,1-f]-purines were synthesized and tested pharmacologically with respect to their influence on the central nervous system. Two of the new compounds induced hypothermia and decreased the spontaneous locomotor activity of mice.