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(R)-N-methyl-1,2,3,4-tetrahydroquinolin-3-amine is an organic compound and a derivative of tetrahydroquinoline. It is a chiral amine characterized by the presence of a methyl group attached to the nitrogen atom and a cyclic structure that includes a tetrahydroquinoline moiety. (R)-N-methyl-1,2,3,4-tetrahydroquinolin-3-amine is distinguished by its specific stereochemical configuration, denoted by the (R)prefix, which refers to the orientation of the substituent groups around the chiral center. This configuration is crucial as it can significantly influence the compound's biological activity and its behavior in chemical reactions.

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  • 166742-75-2 Structure
  • Basic information

    1. Product Name: (R)-N-Methyl-1,2,3,4-tetrahydroquinolin-3-aMine
    2. Synonyms: (R)-N-Methyl-1,2,3,4-tetrahydroquinolin-3-aMine
    3. CAS NO:166742-75-2
    4. Molecular Formula: C10H14N2
    5. Molecular Weight: 162.23156
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 166742-75-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 297.3±29.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.06±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 9.22±0.20(Predicted)
    10. CAS DataBase Reference: (R)-N-Methyl-1,2,3,4-tetrahydroquinolin-3-aMine(CAS DataBase Reference)
    11. NIST Chemistry Reference: (R)-N-Methyl-1,2,3,4-tetrahydroquinolin-3-aMine(166742-75-2)
    12. EPA Substance Registry System: (R)-N-Methyl-1,2,3,4-tetrahydroquinolin-3-aMine(166742-75-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 166742-75-2(Hazardous Substances Data)

166742-75-2 Usage

Uses

Used in Medicinal Chemistry and Drug Discovery:
(R)-N-methyl-1,2,3,4-tetrahydroquinolin-3-amine is utilized as a building block in the synthesis of various bioactive molecules. Its unique structure and chiral properties make it a valuable component in the development of new pharmaceuticals, contributing to the creation of innovative treatments and therapeutic agents.
Used in Pharmaceutical Development:
Due to its ability to interact with biological systems, (R)-N-methyl-1,2,3,4-tetrahydroquinolin-3-amine has potential pharmaceutical uses. The specific stereochemistry of the molecule allows for targeted interactions with biological targets, which can be leveraged to develop drugs with enhanced efficacy and selectivity. This makes it a promising candidate for further research and development in the pharmaceutical industry.

Check Digit Verification of cas no

The CAS Registry Mumber 166742-75-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,6,7,4 and 2 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 166742-75:
(8*1)+(7*6)+(6*6)+(5*7)+(4*4)+(3*2)+(2*7)+(1*5)=162
162 % 10 = 2
So 166742-75-2 is a valid CAS Registry Number.

166742-75-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name (3R)-N-methyl-1,2,3,4-tetrahydroquinolin-3-amine

1.2 Other means of identification

Product number -
Other names (R)-N-Methyl-1,2,3,4-tetrahydroquinolin-3-amine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:166742-75-2 SDS

166742-75-2Relevant articles and documents

HETEROCYCLIC AMINES HAVING CENTRAL NERVOUS SYSTEM ACTIVITY

-

, (2008/06/13)

Tricyclic nitrogen containing compounds, having anxiolytic and anti-depressant activity and central nervous system activity of the following structural formula: and pharmaceutically acceptable salts thereof wherein R1 and R2 are inde

Synthesis of the Selective D2 Receptor Agonist PNU-95666E from D-Phenylalanine Using a Sequential Oxidative Cyclization Strategy

Romero, Arthur G.,Darlington, William H.,McMillan, Moses W.

, p. 6582 - 6587 (2007/10/03)

Compound 1 (PNU-95666E) is a selective and high-affinity agonist at the dopamine D2 receptor subtype and is of interest as a potential agent for the treatment of Parkinson's disease. Requiring a synthetic route amenable to scale-up, a synthesis

Heterocyclic amines having central nervous system activity

-

, (2008/06/13)

Tricyclic nitrogen containing compounds, having anxiolytic and anti-depressant activity and central nervous system activity of the following structural formula: STR1 and pharmaceutically acceptable salts thereof wherein R1 and R2 are

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