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1668565-74-9

IDO-IN-2 is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1668565-74-9 Structure

  • Basic information

    1. Product Name: IDO-IN-2
    2. Synonyms: DO-IN-2
    3. CAS NO:1668565-74-9
    4. Molecular Formula: C29H35N7O
    5. Molecular Weight: 497.6345
    6. EINECS: -0
    7. Product Categories: N/A
    8. Mol File: 1668565-74-9.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.206±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 4.17±0.10(Predicted)
    10. CAS DataBase Reference: IDO-IN-2(CAS DataBase Reference)
    11. NIST Chemistry Reference: IDO-IN-2(1668565-74-9)
    12. EPA Substance Registry System: IDO-IN-2(1668565-74-9)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1668565-74-9(Hazardous Substances Data)

1668565-74-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1668565-74-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,6,8,5,6 and 5 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1668565-74:
(9*1)+(8*6)+(7*6)+(6*8)+(5*5)+(4*6)+(3*5)+(2*7)+(1*4)=229
229 % 10 = 9
So 1668565-74-9 is a valid CAS Registry Number.

1668565-74-9Downstream Products

1668565-74-9Relevant articles and documents

Development of a series of novel o-phenylenediamine-based indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors

Williams, David K.,Markwalder, Jay A.,Balog, Aaron J.,Chen, Bin,Chen, Libing,Donnell, Jennifer,Haque, Lauren,Hart, Amy C.,Mandal, Sunil K.,Nation, Andrew,Shan, Weifang,Vite, Gregory D.,Covello, Kelly,Hunt, John T.,Jure-Kunkel, Maria N.,Seitz, Steven P.

, p. 732 - 736 (2018/02/12)

A novel series of o-phenylenediamine-based inhibitors of indoleamine 2,3-dioxygenase (IDO) has been identified. IDO is a heme-containing enzyme, overexpressed in the tumor microenvironment of many cancers, which can contribute to the suppression of the host immune system. Synthetic modifications to a previously described diarylether series resulted in an additional degree of molecular diversity which was exploited to afford compounds that demonstrated significant potency in the HeLa human cervical cancer IDO1 assay..

IDO INHIBITORS

-

, (2015/03/16)

There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or autoimmune diseases utilizing the compounds of the invention.

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