cas 16689-02-4, 5-Nitrothiophene-2-carbonitrile

Articles about 16689-02-4Total 11 be found

Cascade Process for Direct Transformation of Aldehydes (RCHO) to Nitriles (RCN) Using Inorganic Reagents NH2OH/Na2CO3/SO2F2 in DMSO
A simple, mild, and practical process for direct conversion of aldehydes to nitriles was developed feathering a wide substrate scope and great functional group tolerability (52 examples, over 90% yield in most cases) using inorganic reagents (NH2OH/Na2CO3/SO2F2) in DMSO. This method allows for transformations of readily available, inexpensive, and abundant aldehydes to highly valuable nitriles in a pot, atom, and step-economical manner without transition metals. This protocol will serve as a robust tool for the installation of cyano-moieties to complicated molecules.
Fang, Wan-Yin,Qin, Hua-Li
p. 5803 - 5812
(2019/05/14)

An unexpected involvement of ethyl-2-cyano-2-(hydroxyimino) acetate cleaved product in the promotion of the synthesis of nitriles from aldoximes: A mechanistic perception
While attempting to synthesize nitriles from aldoximes using O-sulfonate esters of oxyma [ethyl 2-cyano-2-(hydroxyimino)acetate], an unexpected involvement of oxyma cleaved product in promoting the synthesis of nitriles was observed. Such involvement of the oxyma cleaved product in the reaction mechanism, together with the usual anticipated pathway improved drastically the applicability of the method by reducing the time needed for the reaction to be completed over that of the sulfonyl chlorides. Other advantages of the present protocol are excellent yields in ambient and milder conditions.
Dev, Dharm,Palakurthy, Nani Babu,Kumar, Nitesh,Mandal, Bhubaneswar
supporting information
p. 4397 - 4400
(2013/07/26)

An efficient synthesis of nitriles from aldoximes using diethyl phosphorocyanidate under mild conditions
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Lee, Kieseung,An, Hyeon-Seong,Hwang, Chan-Yeon
p. 3173 - 3174,2
(2020/09/16)

Compromise between conjugation length and charge-transfer in nonlinear optical η5-monocyclopentadienyliron(II) complexes with substituted oligo-thiophene nitrile ligands: Synthesis, electrochemical studies and first hyperpolarizabilities
A systematic series of η5-monocyclopentadienyliron(II) complexes with substituted oligo-thiophene nitrile ligands of general formula [FeCp(P_P)(NC{SC4H2}nNO2)][P F6] (P_P = dppe, (+)-diop;
Garcia, M. Helena,Mendes, Paulo J.,Robalo, M. Paula,Dias, A. Rom?o,Campo, Jochen,Wenseleers, Wim,Goovaerts, Etienne
p. 3027 - 3041
(2008/02/02)

Efficient transformation of aldoximes to nitriles using 2-chloro-1-methylpyridinium iodide under mild conditions
Various (aliphatic, aromatic, and heterocyclic aromatic) types of aldoximes were converted into the corresponding nitriles in good to excellent yields using 2-chloro-1-methylpyridinium iodide (CMPI) as a dehydrating agent under mild conditions.
Lee, Kieseung,Han, Sang-Bae,Yoo, Eun-Mi,Chung, Soon-Ryang,Oh, Haibum,Hong, Sungwan
p. 1775 - 1782
(2007/10/03)

One-pot synthesis of nitriles from aldehydes under microwave irradiation: Influence of the medium and mode of microwave irradiation on product formation
Chemoselective transformation of aldehyde to nitrile takes place in a one-pot reaction by treatment with H2NOHHCl in N- methyl-2-pyrrolidinone (NMP) under microwave irradiation using convection mode.
Chakraborti, Asit K.,Kaur, Gurmeet
p. 13265 - 13268
(2007/10/03)

Elimination reactions of (Z)-thiophene- and (Z)-furan-2-carbaldehyde O- benzoyloximes. Effect of β-aryl group upon the nitrile-forming anti transition state
Elimination reactions of (Z)-thiophene- and (Z)-furan-2-carbaldehyde O- benzoyloximes 1 and 2 with DBU in MeCN have been investigated kinetically. The reactions are second order and exhibit substantial values of Hammett ρ and k(H)/k(D) values, and an E2 m
Cho, Bong Rae,Cho, Nam Soon,Song, Sang Hun,Lee, Sang Kook
p. 8304 - 8309
(2007/10/03)

A convenient one-pot preparation of nitriles from aldoximes using 2,2'-oxalyldi(o-sulfobenzimide)
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Kitagawa,Kawaguchi,Iwasaki
p. 2583 - 2585
(2007/10/02)

A Useful Method for the Conversion of Aldehyde Oximes into Nitriles Using 1,1'-Oxalyldiimidazole
Under neutral conditions, aliphatic, alicyclic, aromatic, and heteroaromatic aldehyde oximes (3) react with 1,1'-oxalyldiimidazole (2) in an appropriate solvent such as benzene, acetonitrile, chloroform, or tetrahydrofuran at 65-70 degC within 1 h to give the corresponding nitriles (4) in good yield.Keywords --- dehydration; 1,1'-carbonyldiimidazole; 1,1'-oxalyldiimidazole; oxime; nitrile
Kitagawa, Tokujiro,Sasaki, Hideaki,Ono, Noriyuki
p. 4014 - 4016
(2007/10/02)

SYNTHESIS AND REACTIONS OF TRIMETHYLAMMONIUM SALTS OF 5-NITRO-2-FURAN AND 5-NITRO-2-THIOPHENE. THE PREPARATION OF 5-NITRO-2-FURYL- AND 5-NITRO-2-THIENYL AZIDE
Preparation of new water-soluble derivatives of 5-nitro-2-furan and 5-nitro-2-thiophene from 2-bromo-5-nitrofuran (Ia) or 2-bromo-5-nitrothiophene (Ib) and trimethylamine is described.The trimethylammonium derivatives IIa, IIb react with the azide or cyan
Vegh, Daniel,Kovac, Jaroslav,Dandarova, Miloslava
p. 1885 - 1890
(2007/10/02)

INVESTIGATION OF THE KINETICS OF THE NITRATION OF THIOPHENE DERIVATIVES
The kinetics of the nitration of thiophene derivatives with nitric acid in acetic anhydride were investigated.The nitration of 2-substituted thiophenes is a second-order reaction.The rate constants and activation parameters of the reaction were calculated.The possibility of the Hammett and Yukawa-Tsuno equations for this reaction series is demonstrated.An isokinetic dependence is observed.
Freidlin, G. N.,Glushkova, A. A.,Solop, K. A.
p. 127 - 130
(2007/10/02)