Cu-Catalyzed cascades to carbocycles: Union of diaryliodonium salts with alkenes or alkynes exploiting remote carbocations
Copper-catalyzed cascade reactions between alkenes or alkynes and diaryliodonium salts form carbocyclic products in a single step. Arylation of the unsaturated functional group is proposed to form a carbocation intermediate that facilitates hydride shift pathways to translocate the positive charge to a remote position and enables ring formation via a Friedel-Crafts-type reaction.
Zhang, Fengzhi,Das, Shoubhik,Walkinshaw, Andrew J.,Casitas, Alicia,Taylor, Michael,Suero, Marcos G.,Gaunt, Matthew J.
p. 8851 - 8854
(2014/07/08)
Retinoid-like heterocycles
This invention relates to a compound of formula I STR1 in which T is --CONH-- or --CH CH--;R a and R b are independently C 1-6 alkyl;R c is C 1-6 alkyl or hydrogen; andR is heteroaryl and these compounds are useful in preventing and treating skin disorder
-
(2008/06/13)
More Articles about upstream products of 166978-34-3