167029-78-9Relevant articles and documents
Aza-Payne Rearrangement of Activated 2-Aziridinemethanols and 2,3-Epoxy Amines under Basic Conditions
Ibuka, Toshiro,Nakai, Kazuo,Habashita, Hiromu,Hotta, Yuka,Otaka, Akira,et al.
, p. 2044 - 2058 (2007/10/02)
An aza-Payne rearrangement of activated 2-aziridinemethanols with t-BuOK, NaH, or KH at near 0 deg C in common solvents such as THF, toluene, 1,2-dimethoxyethane, 1,4-dioxane, or a mixed solvent of THF-HMPA followed by quenching at -78 deg C gives the cor
Unprecedented Rearrangement Reaction of 2-Aziridinemethanols with "Lower Order" Lithium Methylcyanocuprate
Ibuka, Toshiro,Nakai, Kazuo,Habashita, Hiromu,Fujii, Nobutaka,Garrido, Fabrice,et al.
, p. 7421 - 7424 (2007/10/02)
Complementary selectivity can be achieved in ring opening reactions of 2-aziridinemethanols by using either the Gilman reagent or lower order cyanocuprate.In the former case, the usual attack of the Gilman reagent to the substrates 1 and 2 results in the