16704-78-2

Basic information

• Product Name: (3-hydroxy-p-tolyl)urea
• Synonyms: (3-hydroxy-p-tolyl)urea;N-(3-Hydroxy-4-methylphenyl)urea;Einecs 240-756-0
• CAS NO: 16704-78-2
• Molecular Formula: C₈H₁₀N₂O₂
• Molecular Weight: 166.1772
• EINECS: 240-756-0
• Mol File: 16704-78-2.mol

Chemical Properties

• Boiling Point: 315 °C at 760 mmHg
• Flash Point: 144.3 °C
• Appearance: /
• Density: 1.335 g/cm³
• Vapor Pressure: 0.000243mmHg at 25°C
• Refractive Index: 1.663
• CAS DataBase Reference: (3-hydroxy-p-tolyl)urea(CAS DataBase Reference)
• NIST Chemistry Reference: (3-hydroxy-p-tolyl)urea(16704-78-2)
• EPA Substance Registry System: (3-hydroxy-p-tolyl)urea(16704-78-2)

Safety Data

• Hazardous Substances Data: 16704-78-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical and Agricultural Chemical Synthesis:
(3-hydroxy-p-tolyl)urea is used as a key intermediate in the synthesis of various pharmaceuticals and agricultural chemicals. Its unique chemical structure allows it to be incorporated into the molecular frameworks of these products, contributing to their efficacy and performance.
Used in Corrosion Inhibition:
3-HPTU is utilized as a corrosion inhibitor in industrial applications. Its ability to form protective layers and reduce the rate of corrosion on metal surfaces makes it a valuable component in coatings and other protective formulations.
Used in Coordination Chemistry as a Ligand:
In the field of coordination chemistry, (3-hydroxy-p-tolyl)urea serves as a ligand, interacting with metal ions to form stable complexes. This application is crucial in the development of new materials with specific properties, such as catalysts, sensors, and other functional materials.
Used in Research and Development:
3-HPTU is also employed in research and development settings, where its chemical properties are explored for potential new applications. Its versatility makes it a candidate for investigation in various chemical and material science projects.

InChI:InChI=1/C8H10N2O2/c1-5-2-3-6(4-7(5)11)10-8(9)12/h2-4,11H,1H3,(H3,9,10,12)

Upstream product

• 5428-54-6 2-methyl-5-nitrophenol 
• 590-28-3 potassium cyanate 
• 2835-95-2 amino-4 hydroxy-2 toluene 

Downstream Products

• 933045-88-6 ethyl 2-(3-hydroxy-4-methylphenylamino)oxazole-4-carboxylate 
• 57839-17-5 [2-(3-Chloro-4-methylamino-phenylamino)-5-hydroxy-4-methyl-phenyl]-urea 
• 57839-18-6 {2-[3-Chloro-4-(2-hydroxy-ethylamino)-phenylamino]-5-hydroxy-4-methyl-phenyl}-urea 
• 56330-93-9 {6-[(Z)-3-Chloro-4-(2-hydroxy-ethylamino)-phenylimino]-4-methyl-3-oxo-cyclohexa-1,4-dienyl}-urea 
• 56330-88-2 (6-{[3-chloro-4-(methylamino)phenyl]imino}-4-methyl-3-oxocyclohexa-1,4-dien-1-yl)urea 
• 55303-62-3 C₁₉H₂₃N₅O₃ 
• 55302-71-1 C₁₈H₂₂N₄O₄ 

Relevant articles and documents

COMPOUNDS AND METHODS FOR THE TREATMENT OF VIRUSES AND CANCER

The present invention relates to compounds according to the formula I: Where Ra is H or an optionally OH-substituted C1-C3 alkyl; R1 is OR1, an optionally substituted C4-12 carbocyclic group which may be saturated or unsaturated (including aromatic) or an optionally substituted heterocyclic group; R1 is an optionally substituted C1-C14 hydrocarbyl group or an optionally substituted heterocyclic group;; R2 , R3 and R4 are each independently H, an optionally substituted C1-C4 alkyl group (preferably CH3, CH2CH3 or CF3), halogen (preferably F, Cl, Br), OR, CN, NO2, a C1-C6 thioether, a C1-C6 thioester group, an optionally substituted CO2R group, an optionally substituted COR group or an optionally substituted OCOR group (preferably R4 is H); R is H or an optionally substituted C1-C6 alkyl group; RHET is an optionally substituted heterocyclic group; and pharmaceutically acceptable salts, solvates or polymorphs thereof.

Agent and method for colouring keratin fibres

The present application relates to a preparation for dyeing keratin fibers which, before use, is mixed with an oxidizing agent and wherein a combination of at least one 4,5-diaminopyrazole derivative of the general formula (II) or its physiologically compatible salts and at least one phenylurea derivative of the general formula (I) or its physiologically compatible salts is contained in a suitable cosmetic carrier, as well as a method for dyeing hair using this preparation.

Nitrated coupler compounds useful in direct dyeing and simultaneous oxidation and direct dyeing of keratinic fibers

A cosmetic composition for application to the hair contains either (a) at least one compound having the formula STR1 wherein: R is hydrogen, alkyl or halogen; and R' is hydrogen, alkyl, hydroxyalkyl, carbamylalkyl, mesylaminoalkyl, aminoalkyl, acylaminoalkyl, monoalkylaminoalkyl, dialkylaminoalkyl, piperidinoalkyl, morpholinoalkyl, carbamoyl, acyl or carbalkoxy; or (b) at least one of said compounds having formula I above and at least one benzene or heterocyclic oxidation base. The invention also relates to new couplers of formula I as well as to new indo compounds which result from the coupling of said compounds with an oxidation base. These cosmetic compositions for application to the hair are useful in direct dyeing, oxidation dyeing or simultaneous oxidation and direct dyeing of said hair.