16727-46-1

Basic information

• Product Name: 2,6-BIS(BENZYLOXY)PYRIDINE
• Synonyms: 2,6-BIS(BENZYLOXY)PYRIDINE
• CAS NO: 16727-46-1
• Molecular Formula: C₁₉H₁₇NO₂
• Molecular Weight: 291.34
• Mol File: 16727-46-1.mol

Chemical Properties

• Boiling Point: 425.7±35.0 °C(Predicted)
• Appearance: /
• Density: 1.155±0.06 g/cm3(Predicted)
• Storage Temp.: Room temperature.
• PKA: 2.61±0.24(Predicted)
• CAS DataBase Reference: 2,6-BIS(BENZYLOXY)PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-BIS(BENZYLOXY)PYRIDINE(16727-46-1)
• EPA Substance Registry System: 2,6-BIS(BENZYLOXY)PYRIDINE(16727-46-1)

Safety Data

• Hazardous Substances Data: 16727-46-1(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
2,6-Bis(benzyloxy)pyridine is used as a building block for the synthesis of various organic compounds. Its nucleophilic nature allows it to participate in a range of organic chemistry reactions, facilitating the creation of complex molecular structures.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2,6-Bis(benzyloxy)pyridine is used as a reagent in the development of new drugs. Its potential pharmacological properties are being studied, including its role as a non-toxic insect repellent, which could lead to the creation of safer and more effective pest control solutions.
Used in Chemical Research:
2,6-Bis(benzyloxy)pyridine is also utilized in chemical research to explore its reactivity and potential applications in the synthesis of novel compounds. Its unique properties make it a valuable tool for understanding and advancing the field of organic chemistry.

Upstream product

• 2402-78-0 2,6-dichloropyridine 
• 100-51-6 benzyl alcohol 

Downstream Products

• 16727-47-2 2,6-bis(benzyloxy)-3-bromopyridine 
• 39954-16-0 2,6-dibenzyloxypyridin-3-ol 

Relevant articles and documents

PROTEIN TYROSINE PHOSPHATASE DEGRADERS AND METHODS OF USE THEREOF

Provided herein are compounds, compositions, and methods useful for degrading protein tyrosine phosphatase, e.g., protein tyrosine phosphatase non-receptor type 2 (PTPN2) and/or protein tyrosine phosphatase non-receptor type 1 (PTPN1), and for treating related diseases favorably responsive to PTPN1 or PTPN2 inhibitor treatment, e.g., a cancer 5 or a metabolic disease.

Photoreductive Removal of O-Benzyl Groups from Oxyarene N-Heterocycles Assisted by O-Pyridine-pyridone Tautomerism

Facile photoreductive protocols have been developed to remove benzyl O-protective groups from oxyarene N-heterocycles at positions capable for 2-/4-O-pyridine-2-/4-pyridone tautomerism. Blue light irradiation, a [Ru] or [Ir] photocatalyst, and ascorbic acid in a water-acetonitrile solution debenzylates a variety of aryl N-heterocycles cleanly and selectively. Ascorbic acid has two functions in the reaction. On the one hand, it protonates the N-heterocycles that reduces their reduction potentials notably and on the other hand it acts as a sacrificial reductant. Reduction potentials and free energy barriers calculated at the CPCM-B3LYP/6-31+G? level can predict the reactivities of the studied substrates.

Herbicidal 2,6-substituted pyridines

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