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2-Thiophenecarboxylicacid,3-amino-4,5-dihydro-,methylester(9CI) is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 167280-87-7 Structure
  • Basic information

    1. Product Name: 2-Thiophenecarboxylicacid,3-amino-4,5-dihydro-,methylester(9CI)
    2. Synonyms: 3-Amino-4,5-dihydro-thiophene-2-carboxylic acid methyl ester;2-Thiophenecarboxylicacid,3-amino-4,5-dihydro-,methylester(9CI)
    3. CAS NO:167280-87-7
    4. Molecular Formula: C6H9NO2S
    5. Molecular Weight: 159.21
    6. EINECS: N/A
    7. Product Categories: CARBOXYLICESTER
    8. Mol File: 167280-87-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-Thiophenecarboxylicacid,3-amino-4,5-dihydro-,methylester(9CI)(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-Thiophenecarboxylicacid,3-amino-4,5-dihydro-,methylester(9CI)(167280-87-7)
    11. EPA Substance Registry System: 2-Thiophenecarboxylicacid,3-amino-4,5-dihydro-,methylester(9CI)(167280-87-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 167280-87-7(Hazardous Substances Data)

167280-87-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 167280-87-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,7,2,8 and 0 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 167280-87:
(8*1)+(7*6)+(6*7)+(5*2)+(4*8)+(3*0)+(2*8)+(1*7)=157
157 % 10 = 7
So 167280-87-7 is a valid CAS Registry Number.

167280-87-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl 4-amino-2,3-dihydrothiophene-5-carboxylate

1.2 Other means of identification

Product number -
Other names F1386-0087

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:167280-87-7 SDS

167280-87-7Relevant articles and documents

Discovery of Inhibitor of Wnt Production 2 (IWP-2) and Related Compounds As Selective ATP-Competitive Inhibitors of Casein Kinase 1 (CK1) δ/?

García-Reyes, Balbina,Witt, Lydia,Jansen, Bj?rn,Karasu, Ebru,Gehring, Tanja,Leban, Johann,Henne-Bruns, Doris,Pichlo, Christian,Brunstein, Elena,Baumann, Ulrich,Wesseler, Fabian,Rathmer, Bernd,Schade, Dennis,Peifer, Christian,Knippschild, Uwe

, p. 4087 - 4102 (2018)

Inhibitors of Wnt production (IWPs) are known antagonists of the Wnt pathway, targeting the membrane-bound O-acyltransferase porcupine (Porcn) and thus preventing a crucial Wnt ligand palmitoylation. Since IWPs show structural similarities to benzimidazol

SUBSTITUTED AZETIDINE DIHYDROTHIENOPYRIDINES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS

-

Page/Page column 22-23, (2019/07/19)

The present invention relates to novel substituted azetidine dihydrothienopyridines with phosphodiesterase inhibitory activity, and to their use in therapy, and to pharmaceutical compositions comprising the compounds and to methods of treating diseases wi

Unprecedented Demonstration of Regioselective SEAr Reaction giving Unsymmetrical Regioregular Oligothiophenes

Moussallem, Chady,Olivier, Simon,Grolleau, Jérémie,Allain, Magali,Mallet, Charlotte,Savitha, Gurunathan,Gohier, Frédéric,Frère, Pierre

supporting information, p. 6510 - 6514 (2016/05/02)

Aromatization of 4-cyano-3-oxotetrahydrothiophene by sulfuryl chloride gives the new building block 4-cyano-3-pyrrolidylthiophene, which forms unsymmetrical regioregular oligothiophenes with a strict alternation of the donor and acceptor groups along the conjugated system. The self-coupling reactions that form the oligomers are shown to proceed by a regioselective electrophilic aromatic substitution mechanism involving a stabilized Wheland intermediate. First alternate: Regioregular oligothiophenes based on the 3-pyrrolidyl-4-cyanothiophene building block, with a strict alternation of the donor and acceptor groups along the conjugated backbone, have been prepared in one step. The mechanism of formation of the oligomers corresponds to a regioselective self-electrophilic aromatic substitution (self-SEAr) involving a stabilized Wheland intermediate.

HIGHLY POTENT INHIBITORS OF PORCUPINE

-

Page/Page column 46, (2014/12/12)

The present invention generally relates to protein signalling. In particular, compounds that inhibit the Wnt protein signalling pathway are disclosed. Such compounds may be used in the treatment of Wnt protein signalling-related diseases and conditions such as cancer, degenerative diseases, type II diabetes and osteopetrosis.

The development of highly potent inhibitors for porcupine

Wang, Xiaolei,Moon, Jesung,Dodge, Michael E.,Pan, Xinchao,Zhang, Lishu,Hanson, Jordan M.,Tuladhar, Rubina,Ma, Zhiqiang,Shi, Heping,Williams, Noelle S.,Amatruda, James F.,Carroll, Thomas J.,Lum, Lawrence,Chen, Chuo

, p. 2700 - 2704 (2013/05/08)

Porcupine is a member of the membrane-bound O-acyltransferase family of proteins. It catalyzes the palmitoylation of Wnt proteins, a process required for their secretion and activity. We recently disclosed a class of small molecules (IWPs) as the first reported Porcn inhibitors. We now describe the structure-activity relationship studies and the identification of subnanomolar inhibitors. We also report herein the effects of IWPs on Wnt-dependent developmental processes, including zebrafish posterior axis formation and kidney tubule formation.

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