167478-82-2

Basic information

• Product Name: methyl 1,5-dimethyl-1H-indole-2-carboxylate
• Synonyms: methyl 1,5-dimethyl-1H-indole-2-carboxylate
• CAS NO: 167478-82-2
• Molecular Formula: C12H13NO2
• Molecular Weight: 203.24
• Mol File: 167478-82-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: methyl 1,5-dimethyl-1H-indole-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 1,5-dimethyl-1H-indole-2-carboxylate(167478-82-2)
• EPA Substance Registry System: methyl 1,5-dimethyl-1H-indole-2-carboxylate(167478-82-2)

Safety Data

• Hazardous Substances Data: 167478-82-2(Hazardous Substances Data)

Upstream product

• 10241-97-1 5-methylindole-2-carboxylic acid 
• 74-88-4 methyl iodide 
• 102870-03-1 5-methylindole-2-carboxylic acid methyl ester 

Downstream Products

• 883526-76-9 1,5-dimethyl-1H-indole-2-carbaldehyde 
• 1305306-37-9 C₂₁H₁₉N 

Relevant articles and documents

From far west to east: Joining the molecular architecture of imidazole-like ligands in ho-1 complexes

HO-1 overexpression has been reported in several cases/types of human malignancies. Unfortunately, poor clinical outcomes are reported in most of these cases, and the inhibition of HO-1 is considered a valuable and proven anticancer approach. To identify

Visible-Light-Promoted Oxidative [4 + 2] Cycloadditions of Aryl Silyl Enol Ethers

Visible-light-promoted oxidative [4 + 2] cycloadditions of μ,3-unsaturated silyl enol ethers have been developed to efficiently and diastereoselectively construct polycyclic skeletons under mild conditions. The diastereoselectivities were dependent on the stereoconfiguration of silyl enol ether, substitutions on the link, as well as electric properties of substitutions on aryl rings. The intermediates could be trapped by TEMPO, oxygen or methanol. Mechanistic studies indicated the reaction was initiated by one-electron oxidation of the silyl enol ether.

Synthesis of carbazoles by gold(I)-catalyzed carbocyclization of 2-(enynyl)indoles

A new synthetic protocol for carbazoles through gold(I)-catalyzed intramolecular hydroarylation of (Z)-2-(enynyl)indoles was achieved in good yields. The requisite (Z)-2-(enynyl)indoles were synthesized stereoselectively by trimethylgallium-promoted, Z-selective Wittig olefination of N-alkylindole-2-carboxaldehydes with propargyl ylides. Substrates possessing both alkyl as well as aromatic groups are well tolerated under these reaction conditions. Georg Thieme Verlag Stuttgart.