169106-34-7

Basic information

• Product Name: S-2-Aminododecanoic acid
• Synonyms: S-2-Aminododecanoic acid;S-dodecyline;S-dodecyline S-2-AMinododecanoic acid;(2S)-2-Amino-dodecanoic acid
• CAS NO: 169106-34-7
• Molecular Formula: C12H25NO2
• Molecular Weight: 215.3324
• Mol File: 169106-34-7.mol

Chemical Properties

• Boiling Point: 332.8±25.0 °C(Predicted)
• Appearance: /
• Density: 0.955±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 2.55±0.24(Predicted)
• CAS DataBase Reference: S-2-Aminododecanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: S-2-Aminododecanoic acid(169106-34-7)
• EPA Substance Registry System: S-2-Aminododecanoic acid(169106-34-7)

Safety Data

• Hazardous Substances Data: 169106-34-7(Hazardous Substances Data)

Usage

Uses

Used in Enhanced Oil Recovery:
S-2-Aminododecanoic acid is used as a biosurfactant in enhanced oil recovery processes to improve the efficiency of oil extraction. Its amphiphilic nature helps reduce the interfacial tension between oil and water, facilitating the mobilization of trapped oil and increasing the overall oil recovery rate.
Used in Bioremediation:
In bioremediation applications, S-2-Aminododecanoic acid serves as a biosurfactant to enhance the bioavailability of contaminants, making them more accessible to microorganisms for degradation. This improves the efficiency of biodegradation processes and contributes to the cleanup of contaminated environments.
Used as an Antimicrobial Agent:
S-2-Aminododecanoic acid is used as an antimicrobial agent due to its ability to disrupt the cell membranes of microorganisms, inhibiting their growth and effectively controlling microbial populations in various settings.
Used in Cosmetics and Personal Care Products:
In the cosmetics and personal care industry, S-2-Aminododecanoic acid is used as an emulsifying agent and surfactant. Its amphiphilic properties allow it to stabilize emulsions and improve the texture and performance of various products, such as creams, lotions, and shampoos.
Used in Food Industry:
In the food industry, S-2-Aminododecanoic acid can be used as a food additive to improve the stability and texture of food products. Its surfactant properties can help create stable emulsions and foams, enhancing the sensory properties and shelf life of certain foods.
Used in Pharmaceutical Industry:
S-2-Aminododecanoic acid can be utilized in the pharmaceutical industry as a solubilizing agent for poorly water-soluble drugs. Its amphiphilic nature can improve the solubility and bioavailability of certain pharmaceutical compounds, potentially enhancing their therapeutic efficacy.

Upstream product

• 35237-37-7 2-amino-dodecanoic acid 
• 205385-74-6 2-(2-chloro-acetylamino)-dodecanoic acid 
• 92329-14-1 N-Dichloracetyl-DL-2-amino-laurinsaeure 
• 13880-54-1 (+/-)-2-amino-dodecanoic acid amide 

Relevant articles and documents

Clarification of the binding mode of teleocidin and benzolactams to the Cys2 domain of protein kinase Cδ by synthesis of hydrophobically modified, teleocidin-mimicking benzolactams and computational docking simulation

Phorbol esters (12-O-tetradecanoylphorbol 13-acetate; TPA) and teleocidins are known to be potent tumor promoters and to activate protein kinase C (PKC) by binding competitively to the enzyme. The relationship between the chemical structures and the activities of these compounds has attracted much attention because of the marked structural dissimilarities. The benzolactam 5, with an eight-membered lactam ring and benzene ring instead of the nine-membered lactam ring and indole ring of teleocidins, reproduces the active ring conformation and biological activities of teleocidins. Herein we describe the synthesis of benzolactams with hydrophobic substituents at various positions. Structure-activity data indicate that the existence of a hydrophobic region between C-2 and C-9 and the steric factor at C-8 play critical roles in the appearance of biological activities. We also computationally simulated the docking of teleocidin and the modified benzolactam molecules to the Cys2 domain structure observed in the crystalline complex of PKCδ with phorbol 13-acetate. Teleocidin and benzolactams fitted well into the same cavity as phorbol 13-acetate. Of the three functional groups hydrogenbonding to the protein, two hydrogen-bonded with protein atoms in common with phorbol 13-acetate, but the third one hydrogen-bonded with a different protein atom from that in the case of phorbol 13-acetate. The model explains well the remarkable difference in activity between 5 and its analogue having a bulky substituent at C-8.