169213-73-4

Basic information

• Product Name: (3-(trifluoroMethyl)-1H-pyrazol-5-yl)Methanol
• Synonyms: (3-(trifluoroMethyl)-1H-pyrazol-5-yl)Methanol;(5-(trifluoromethyl)-1H-pyrazol-3-yl)methanol
• CAS NO: 169213-73-4
• Molecular Formula: C5H5F3N2O
• Molecular Weight: 166.1012096
• EINECS: -0
• Mol File: 169213-73-4.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• Solubility: DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: (3-(trifluoroMethyl)-1H-pyrazol-5-yl)Methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (3-(trifluoroMethyl)-1H-pyrazol-5-yl)Methanol(169213-73-4)
• EPA Substance Registry System: (3-(trifluoroMethyl)-1H-pyrazol-5-yl)Methanol(169213-73-4)

Safety Data

• Hazardous Substances Data: 169213-73-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(3-(trifluoroMethyl)-1H-pyrazol-5-yl)Methanol is used as a building block for the synthesis of various bioactive molecules. Its unique structure and the presence of the trifluoromethyl group make it a valuable component in the development of new pharmaceutical compounds.
Used in Agrochemicals:
(3-(trifluoroMethyl)-1H-pyrazol-5-yl)Methanol may have potential applications in agrochemicals, where its unique properties can be utilized to develop new products for agricultural purposes.
Used in Materials Science:
(3-(trifluoroMethyl)-1H-pyrazol-5-yl)Methanol may also have uses in materials science, where its properties can be explored for the development of new functional materials.

Upstream product

• 129768-30-5 5-trifluoromethyl-2H-pyrazole-3-carboxylic acid ethyl ester 
• 129768-29-2 3-(trifluoromethyl)pyrazole-5-carbonyl chloride 
• 172032-07-4 4,4,5,5,5-pentafluoro-2-iodopent-2-en-1-ol 

Relevant articles and documents

Synthesis of 3-perfluoroalkyl-, including 3-trifluoromethyl-, substituted pyrazoles from perfluoroalkylacetylenes

3-Perfluoroalkylpyrazoles 2 have been prepared in excellent yield by the reactions of perfluoroalkylacetylenes 1 with hydrazine monohydrate under mild conditions. - Keywords: Perfluoroalkylpyrazoles; Synthesis; Perfluoroalkylacetylenes; Hydrazene; Nucleop

PYRAZOLYL SUBSTITUTED TETRAHYDROPYRANYLSULFONES

The invention relates to pyrazolyl substituted tetrahydropyranylsulfones as voltage gated calcium channel blockers, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.

PYRAZOLEALKANAMIDE SUBSTITUTED THIOPHENES AS AMPA POTENTIATORS

The present invention relates to a heterocyclic derivative according to Formula (I) wherein the variables are defined as in the specification, or to a pharmaceutically acceptable salt or solvate thereof. The present invention also relates to a pharmaceuti

Convenient and versatile synthesis of 3-(polyfluoroalkyl)pyrazoles

3-(Polyfluoroalkyl)pyrazoles 4 have been synthesized in excellent yields in a two-step sequence from polyfluoroalkyl iodides 1.The synthesis consisted of the reaction of iodides 1 with enamines or enol ethers to give α-polyfluoroalkyl carbonyl derivatives 3 followed by treatment with hydrazine monohydrate.A practical one-pot synthesis of pyrazoles 4 from iodides 1 gas also been developed and the reaction mechanism is discussed.

A novel and practical method for the synthesis of 3-trifluoromethylated pyrazoles

A new building block strategy for the synthesis of a series of 3-trifluoromethyl substituted pyrazoles 4 by a two-step sequence is described.