169253-08-1

Basic information

• Product Name: 2-(1-Methyl-3-piperidinyl)acetic acid
• Synonyms: 2-(1-Methyl-3-piperidinyl)acetic acid;(1-Methyl-piperidin-3-yl)-acetic acid;1-methyl-3-piperidineacetic acid;1-Methyl-3-piperidineacetic acid HCl;2-(1-METHYLPIPERIDIN-3-YL)ACETIC ACID
• CAS NO: 169253-08-1
• Molecular Formula: C8H15NO2
• Molecular Weight: 157.2102
• Mol File: 169253-08-1.mol

Chemical Properties

• Boiling Point: 269.9±13.0 °C(Predicted)
• Appearance: /
• Density: 1.050±0.06 g/cm3(Predicted)
• PKA: 4.43±0.10(Predicted)
• CAS DataBase Reference: 2-(1-Methyl-3-piperidinyl)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-Methyl-3-piperidinyl)acetic acid(169253-08-1)
• EPA Substance Registry System: 2-(1-Methyl-3-piperidinyl)acetic acid(169253-08-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 169253-08-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-(1-Methyl-3-piperidinyl)acetic acid serves as a key starting material for the synthesis of pharmaceutical drugs, leveraging its chemical structure to create compounds with therapeutic effects.
Used as an Antipsychotic Agent:
In the field of psychiatry, 2-(1-Methyl-3-piperidinyl)acetic acid is used as an antipsychotic agent, potentially aiding in the management of psychotic symptoms by impacting the neurotransmission related to these conditions.
Used as an Analgesic Agent:
2-(1-Methyl-3-piperidinyl)acetic acid is also utilized as an analgesic, meaning it has the capacity to relieve pain, providing an alternative or adjunct to existing pain management therapies.
Used for Inhibiting Neurotransmitter Reuptake:
2-(1-Methyl-3-piperidinyl)acetic acid is applied to inhibit the reuptake of serotonin and norepinephrine, which can enhance the levels of these neurotransmitters in the synaptic cleft, thereby potentially improving mood and cognitive function, and managing conditions like depression and anxiety.
Used in Substance Abuse and Addiction Treatment:
2-(1-Methyl-3-piperidinyl)acetic acid has been investigated for its potential to treat substance abuse and addiction, offering a chemical approach to managing withdrawal symptoms and cravings.
Used in Depression and Anxiety Disorder Treatment:
Furthermore, 2-(1-Methyl-3-piperidinyl)acetic acid has shown promise in the treatment of depression and anxiety disorders, potentially modulating the brain's chemistry to alleviate symptoms and improve the quality of life for affected individuals.

Downstream Products

• 101257-32-3 1-Methyl-3-<2-hydroxy-ethyl>-piperidin 

Relevant articles and documents

CARBONYL-PIPERAZINYL AND PIPERIDINIL COMPOUNDS WHICH INHIBIT FARNESYL PROTEIN TRANSFERASE

Novel carbonyl piperazinyl and piperidinyl compounds of formula (1.0) or (1.1) and pharmaceutical compositions are disclosed. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering the novel carbonyl piperazinyl or piperidinyl compound to a biological system. In particular, the method inhibits the abnormal growth cells in a mammal such as the human being. A compound of formula (1.0) and (1.1) or a pharmaceutically acceptable salt or solvate thereof, wherein Z is a group which is (i), (ii) or (iii), wherein X1 is CH or N; X2 can be the same or different and can be CH, N, or N-O; b is 0, 1, 2, 3, 4; n and nn independently represent 0, 1, 2, 3, 4 or when X2 is CH, n and nn can be 5; R20 and R21, R1, R2 and R3 are as given in the description.

Carbonyl piperazinyl and piperidinyl compounds

Novel carbonyl piperazinyl and piperidinyl compounds and pharmaceutical compositions are disclosed. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering the novel carbonyl piperazinyl or piperidinyl compound to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammal such as a human being.

Tricyclic compounds

Novel compounds of Formula STR1 are disclosed. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering a compound of the formula to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammal such as a human being.

Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases

A method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells is disclosed. The method comprises the administration of a compound of Formula 1.0: STR1 to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammal such as a human being. Novel compounds of formulas 5.0, 5.1 and 5.2, wherein R is --C(R20)(R21)(R46), and 5.3, 5.3A and 5.3B, wherein R is --N(R25)(R48), are disclosed. Also disclosed are processes for making 3-substituted compounds of Formulas 5.0, 5.1, 5.2 and 5.3. Further disclosed are novel compounds which are intermediates in the process for making 3-substituted compounds of Formulas 5.0, 5.1, 5.2 and 5.3.

Tricyclic compounds useful for inhibition of G-protein function and for treatment of proliferative diseases

Novel compounds of Formula STR1 are disclosed. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering a compound of the Formula 1.0 to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammal such as a human being.

Tricyclic amide and urea compounds useful for inhibition of G-protein function and for treatment of proliferative diseases

Novel compounds of Formula (7.0a), (7.0b) or (7.0c): STR1 are disclosed. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering a compound of the formula (7.0a), (7.0b) or (7.0c) to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammal such as a human being.