An ortho-directing effect in the nucleophilic aromatic substitution reactions of primary and secondary 2,4-dichloro- and 2,3,4-trichlorobenzamides with ethanethiolate
The reactions of the primary amide and several secondary amides of 2,4-dichloro- and 2,3,4-trichlorobenzoic acid with potassium ethanethiolate in DMF were observed to proceed with a remarkable degree of ortho-regioselectivity. This effect was found to be
SUBSTITUTED PYRIDINEAMIDE COMPOUNDS USEFUL AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS
Disclosed are compounds active against soluble epoxide hydrolase (sEH), compositions thereof and methods of using and making same.
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Page/Page column 72
(2008/06/13)
SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHODS OF USING SAME
Disclosed are compounds active against soluble epoxide hydrolase (sEH), compositions thereof and methods of using and making same.
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Page/Page column 106
(2008/06/13)
Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones
A method for producing an alkylthiobenzamide by carrying out a reaction of a halobenzamide with an alkanethiol in the presence of a base in a heterogeneous solvent; a method for producing an alkylsulfinylbenzamide by carrying out a reaction of an alkylthi
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(2008/06/13)
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