The invention discloses 2 -trifluoromethyl -4 - amino - quinoline derivatives and application thereof, and comprises a compound represented by the following general formula I. The prepared compound is used for preparing an anti-tumor active drug, has a go
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Paragraph 0032-0036; 0140-0144
(2021/11/10)
A convenient synthesis of 2-(F-alkyl)-4-hydroxyquinolines
A convenient new route to 2-(F-alkyl)-4-hydroxyquinolines has been developed.In the presence of triethylamine, treatment of ethyl 2,2-dihydropolyfluoroalkanoates with aromatic amines in acetonitrile at 70 deg C led to a mixture of the corresponding enamin
Huang, Wei-Yuan,Liu, Yan-Song,Lu, Long
p. 209 - 214
(2007/10/02)
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