25-Hydroxyvitamin D3 3-Glucuronide is a glucuronidated conjugate of 5-Hydroxyvitamin D3 (C125700), which is the principal circulating form of vitamin D3. 25-HydroxyvitaMin D3 3-Glucuronide is formed in the liver through hydroxylation at the C-25 position and plays a crucial role in regulating calcium levels in the body.

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Basic information
1. Product Name: 25-HydroxyvitaMin D3 3-Glucuronide
2. Synonyms: 25-HydroxyvitaMin D3 3-Glucuronide;25-HydroxyvitaMin D3 3-Glucuronide >90%;RYOQRDXVFJRWFJ-AHYWSSLSSA-N
3. CAS NO:170512-14-8
4. Molecular Formula: C33H52O8
5. Molecular Weight: 576.76118
6. EINECS: N/A
7. Product Categories: Chiral Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
8. Mol File: 170512-14-8.mol
Chemical Properties
1. Melting Point: N/A
2. Boiling Point: N/A
3. Flash Point: N/A
4. Appearance: /
5. Density: N/A
6. Refractive Index: N/A
7. Storage Temp.: Amber Vial, -86°C Freezer, Under inert atmosphere
8. Solubility: DMSO (Slightly), Methanol (Slightly)
9. Stability: Light Sensitive, Hygroscopic
10. CAS DataBase Reference: 25-HydroxyvitaMin D3 3-Glucuronide(CAS DataBase Reference)
11. NIST Chemistry Reference: 25-HydroxyvitaMin D3 3-Glucuronide(170512-14-8)
12. EPA Substance Registry System: 25-HydroxyvitaMin D3 3-Glucuronide(170512-14-8)
Safety Data
1. Hazard Codes: N/A
2. Statements: N/A
3. Safety Statements: N/A
4. WGK Germany:
5. RTECS:
6. HazardClass: N/A
7. PackingGroup: N/A
8. Hazardous Substances Data: 170512-14-8(Hazardous Substances Data)

170512-14-8 Usage

Uses

Used in Pharmaceutical Industry:
25-Hydroxyvitamin D3 3-Glucuronide is used as a calcium regulator for maintaining proper calcium homeostasis in the body. It is essential for various physiological processes, including bone metabolism, immune system function, and cellular differentiation.
Used in Nutritional Supplements:
As a vital component of vitamin D3, 25-Hydroxyvitamin D3 3-Glucuronide is used in the development of nutritional supplements to ensure adequate levels of this essential nutrient in the human diet. This helps in preventing vitamin D deficiency and its associated health issues, such as rickets, osteoporosis, and immune system dysfunction.
Used in Research and Development:
25-Hydroxyvitamin D3 3-Glucuronide is also utilized in research and development for studying the role of vitamin D in various biological processes and its potential therapeutic applications in treating diseases related to calcium metabolism and immune function.

Check Digit Verification of cas no

The CAS Registry Mumber 170512-14-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,0,5,1 and 2 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 170512-14:
(8*1)+(7*7)+(6*0)+(5*5)+(4*1)+(3*2)+(2*1)+(1*4)=98
98 % 10 = 8
So 170512-14-8 is a valid CAS Registry Number.

170512-14-8Upstream product

170512-14-8Downstream Products

170512-14-8Relevant articles and documents

In vitro glucuronidation of 25-hydroxyvitamin D3 and its pro-form

Shimada, Kazutake,Kamezawa, Yuko,Mitamura, Kuniko

, p. 596 - 600 (1997)

In vitro glucuronidation of 25-hydroxyvitamin D3 and its pro-form has been investigated by means of HPLC with UV detection. Although both substrates gave 3- and 25-glucuronides in the presence of the rat liver microsomal fraction and uridine-5'

Syntheses and enzymatic hydrolysis of 25-hydroxyvitamin D monoglucuronides

Shimada,Sugaya,Kaji,Nakatani,Mitamura,Tsutsumi

, p. 1379 - 1384 (2007/10/02)

25-Hydroxyvitamin D3 (D2) 3- and 25-monoglucuronides were synthesized from the corresponding provitamin D or its derivatives with the Koenigs- Knorr reaction using silver carbonate as a catalyst, followed by photochemical reaction, t

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CAS

170512-14-8