Welcome to LookChem.com Sign In|Join Free

CAS

  • or

1706460-52-7

5-(benzyloxy)pyrazolo[1,5-a]pyridine-3-carboxylic acid is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1706460-52-7 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 1706460-52-7 Structure

  • Basic information

    1. Product Name: 5-(benzyloxy)pyrazolo[1,5-a]pyridine-3-carboxylic acid
    2. Synonyms: 5-(benzyloxy)pyrazolo[1,5-a]pyridine-3-carboxylic acid
    3. CAS NO:1706460-52-7
    4. Molecular Formula: C15H12N2O3
    5. Molecular Weight: 268.26738
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1706460-52-7.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 5-(benzyloxy)pyrazolo[1,5-a]pyridine-3-carboxylic acid(CAS DataBase Reference)
    10. NIST Chemistry Reference: 5-(benzyloxy)pyrazolo[1,5-a]pyridine-3-carboxylic acid(1706460-52-7)
    11. EPA Substance Registry System: 5-(benzyloxy)pyrazolo[1,5-a]pyridine-3-carboxylic acid(1706460-52-7)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1706460-52-7(Hazardous Substances Data)

1706460-52-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1706460-52-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,7,0,6,4,6 and 0 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1706460-52:
(9*1)+(8*7)+(7*0)+(6*6)+(5*4)+(4*6)+(3*0)+(2*5)+(1*2)=157
157 % 10 = 7
So 1706460-52-7 is a valid CAS Registry Number.

1706460-52-7Downstream Products

1706460-52-7Relevant articles and documents

Structure-activity relationship study of EphB3 receptor tyrosine kinase inhibitors

Qiao, Lixin,Choi, Sungwoon,Case, April,Gainer, Thomas G.,Seyb, Kathleen,Glicksman, Marcie A.,Lo, Donald C.,Stein, Ross L.,Cuny, Gregory D.

supporting information; experimental part, p. 6122 - 6126 (2010/06/16)

A structure-activity relationship study for a 2-chloroanilide derivative of pyrazolo[1,5-a]pyridine revealed that increased EphB3 kinase inhibitory activity could be accomplished by retaining the 2-chloroanilide and introducing a phenyl or small electron donating substituents to the 5-position of the pyrazolo[1,5-a]pyridine. In addition, replacement of the pyrazolo[1,5-a]pyridine with imidazo[1,2-a]pyridine was well tolerated and resulted in enhanced mouse liver microsome stability. The structure-activity relationship for EphB3 inhibition of both heterocyclic series was similar. Kinase inhibitory activity was also demonstrated for representative analogs in cell culture. An analog (32, LDN-211904) was also profiled for inhibitory activity against a panel of 288 kinases and found to be quite selective for tyrosine kinases. Overall, these studies provide useful molecular probes for examining the in vitro, cellular and potentially in vivo kinase-dependent function of EphB3 receptor.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 1706460-52-7