170654-39-4

Basic information

• Product Name: Ethanone, 1-cyclohexyl-2,2-difluoro-2-(methylthio)- (9CI)
• Synonyms: Ethanone, 1-cyclohexyl-2,2-difluoro-2-(methylthio)- (9CI)
• CAS NO: 170654-39-4
• Molecular Formula: C9H14F2OS
• Molecular Weight: 208.2686664
• Product Categories: ACETYLHALIDE
• Mol File: 170654-39-4.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Ethanone, 1-cyclohexyl-2,2-difluoro-2-(methylthio)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-cyclohexyl-2,2-difluoro-2-(methylthio)- (9CI)(170654-39-4)
• EPA Substance Registry System: Ethanone, 1-cyclohexyl-2,2-difluoro-2-(methylthio)- (9CI)(170654-39-4)

Safety Data

• Hazardous Substances Data: 170654-39-4(Hazardous Substances Data)

Upstream product

• 2043-61-0 cyclohexanecarbaldehyde 

Relevant articles and documents

Fluorination of Orthothioesters through Oxidative Desulfurization-Fluorination

The oxidative desulfurization-fluorination of orthothioesters of type RCH2C(SMe)3 using n-Bu4NH2F3 and 1,3-dibromo-5,5-dimethylhydantoin gave bromodifluorination products RCHBrCF2SMe in good yields. The products were converted into bromodifluoro olefins RCBr=CF2 via oxidation and thermolysis. In a similar way, the orthothioesters of type RCH(OH)C(SMe)3 or RCH(OAc)C(SMe)3 were fluorinated to afford difluoro ketones RCOCF2SMe or difluoro acetates RCH(OAc)CF2SMe, respectively. The difiuoro acetates were reduced to RCH(OAc)CF2H by radical reduction. The mechanisms are discussed for difluorination accompanied by bromination or oxidation.

Oxidative Desulfurization-Fluorination of 1-Substituted 2,2,2-Tris(methylthio)ethanol Induces Difluorination under Oxidation or Rearrangement

Oxidative desulfurization-fluorination of RCH(OH)C(SMe)3 using n-Bu4NH2F3 and 1,3-dibromo-5,5-dimethylhydantoin gave RC(O)CF2SMe, whereas treatment of the same substrates with Et2NSF3 afforded RCH(SMe)CF2SMe.